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临床试验/NCT05373836
NCT05373836已完成不适用

Relationship of PNI and Clinical Outcome in Patients Undergoing Brain Tumor Surgery

Seoul National University Hospital1 个研究点 分布在 1 个国家目标入组 3,263 人开始时间: 2024年12月12日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
3,263
试验地点
1
主要终点
predictability of prognostic nutritional index for mortality after brain tumor surgery

研究概览

简要总结

There are several predictors of clinical outcome in patients undergoing brain tumor surgery. Among those, nutritional parameters and calculated nutritional index are known to have ability to predict mortality and clinical outcomes in some patients with brain tumor. However, there are lack of consistent results on predictability of nutritional index and clinical outcome in patients undergoing brain tumor surgery.

详细描述

In this retrospective study, we evaluated the relationship between prognostic nutritional index, which was calculated from laboratory parameters, and clinical outcome including mortality in patients undergoing brain tumor surgery.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • adult patients undergoing brain tumor surgery at Seoul National University Hospital, South Korea

排除标准

  • Lack of results of laboratory parameters, such as serum albumin, lymphocyte count, cholesterol
  • Lack of data on clinical outcome, including mortality, acute kidney injury, renal replacement therapy, length of hospital stay, and other major adverse outcome

研究组 & 干预措施

brain tumor surgery

adult patients undergoing brain tumor surgery

干预措施: prognostic nutritional index calculated from laboratory parameters (Diagnostic Test)

结局指标

主要结局

predictability of prognostic nutritional index for mortality after brain tumor surgery

时间窗: From date of surgery until the date of death from any cause, whichever came first, assessed up to 50 years

Odds ratio of prognostic nutritional index for postoperative mortality

次要结局

  • predictability of prognostic nutritional index for renal replacement therapy after brain tumor surgery(From date of surgery until the date of renal replacement therapy from any cause, whichever came first, assessed up to 50 years)
  • relationship of prognostic nutritional index for length of hospital stay after brain tumor surgery(From date of surgery until the date of hospital discharge)
  • predictability of prognostic nutritional index for acute kidney injury after brain tumor surgery(From date of surgery until the date of acute kidney injury from any cause, whichever came first, assessed up to 50 years)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Youn Joung Cho, MD, PhD

Clinical Associate Professor

Seoul National University Hospital

研究点 (1)

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