Logistic Organ Dysfunction System Role in Predicting 30-day Mortality Outcome in Intensive Care Unit of dr. Cipto Mangunkusumo General Hospital Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 439
- 试验地点
- 1
- 主要终点
- Correlation between LODS score variables with patient outcome
研究概览
简要总结
LODS score for deceased ICU patients within 30 days is higher than survived ICU patients
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patient (age 18 years and above) admitted to ICU
排除标准
- •patients admitted to ICU due to burn injury, coronary artery disease, post cardiac surgery
- •patients with incomplete required information for LODS score
- •patients deceased or discharged less than 24 hours of admission
结局指标
主要结局
Correlation between LODS score variables with patient outcome
时间窗: 30 days from admission
Correlation between patient outcomes with each LODS score variables: GCS; heart rate; systolic BP; blood urea; serum creatinine; urine output; leucocyte count; platelet count; PaO2/FiO2; serum bilirubin; prothrombin time.
LODS score discrimination ability
时间窗: 30 days from admission
LODS score ability to discriminate patient outcomes based on variables of logistic organ dysfunction system scores: GCS; heart rate; systolic BP; blood urea; serum creatinine; urine output; leucocyte count; platelet count; PaO2/FiO2; serum bilirubin; prothrombin time.
LODS score calibration
时间窗: 30 days from admission
LODS score ability to predict patient outcomes based on variables of logistic organ dysfunction system scores: GCS; heart rate; systolic BP; blood urea; serum creatinine; urine output; leucocyte count; platelet count; PaO2/FiO2; serum bilirubin; prothrombin time.
次要结局
- LODS neurologic variable score: Glasgow Coma Scale (GCS)(Day 1)
- LODS cardiovascular variable score: Heart rate (HR) and/or systolic blood pressure (SBP)(Day 1)
- LODS pulmonary variable score: Partial oxygen pressure (PaO2)/Fraction of inspired oxygen (FiO2) on Mechanical Ventilation (MV) or Continuous Positive Airway Pressure (CPAP)(Day 1)
- Patient outcome(30 days from admission)
- LODS hematologic variable score: white blood cell (WBC) count and/or platelet count(Day 1)
- LODS renal variable score: serum urea nitrogen (BUN) and/or creatinine and/or urine output (UO)(Day 1)
- LODS hepatic function variable score: Serum Bilirubin and/or Prothrombin time (PT)(Day 1)
研究者
Dita Aditianingsih
MD, PhD, Anesthesiologist Consultant
Indonesia University