Early detection of insulin resistance with a mixed meal challenge in healthy adults at-risk of insulin resistance - The REFINE Study

Deakin University0 个研究点目标入组 255 人开始时间: 2024年3月22日最近更新: 2024年4月1日

适应症

试验速览

暂无简介。

•1. Fasting blood glucose <= 6.0 mM
•2. 35-75 years old
•PLUS at least one of the below risk factors for insulin resistance:
•i). Overweight/obese (body mass index >=25 kg/m2).
•ii). Elevated blood pressure (defined as seated blood pressure >130/85 mmHg, or on medication to control blood pressure).
•iii). Abnormal blood lipids (fasting triglycerides >1.7 mM, total cholesterol >5.5 mM or high density lipoproteins <1.0 mM for males or <1.3 mM for females, or on medication to treat their lipids).
•iv). Have a parent with type 2 diabetes or a parent with premature onset cardiovascular disease (males <=55 years, females <=65 years).
•v). Prior history of gestational diabetes (for females).

•1. Have type 2 diabetes or elevated fasting blood glucose (> 6.0 mM).
•2. <35 or >75 years old.
•3. On medication known to alter insulin sensitivity or blood glucose levels
•(e.g. metformin, glucocorticoids).
•4. Have cardiovascular disease (e.g. previous heart attack, stroke, pacemaker etc).
•5. Pregnant or lactating.
•6. Lactose/dairy intolerance or people abstaining from dairy.

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