Combined Effect of Aerobic and Resistance Exercise in Non Ischemic Dilated Cardiomyopathy Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 66
- 试验地点
- 2
- 主要终点
- Functional Independence Measure (FIM) questionnaire
研究概览
简要总结
This study explores the effects of combined aerobic and resistance exercise in patients with non-ischemic dilated cardiomyopathy (NIDCM). In a six-week randomized clinical trial with 66 participants, both exercise groups-combined and aerobic-only-showed significant improvements in exercise capacity, functional independence, dyspnea, and blood pressure. However, no significant difference was found between the two groups. The study concludes that both exercise approaches are effective, but longer studies are needed to determine if combined training offers added benefits.
详细描述
The study titled "Combined Effect of Aerobic and Resistance Exercise in Non-Ischemic Dilated Cardiomyopathy Patients" by Arooj Fatima investigates how integrating both aerobic and resistance exercises impacts patients suffering from NIDCM, a condition marked by left ventricular dysfunction and reduced exercise tolerance. Through a randomized clinical trial involving 66 patients divided into two groups-one receiving both aerobic and resistance training and the other only aerobic training-the study evaluated changes in ejection fraction, VO₂ max, dyspnea, and functional independence over six weeks. Significant improvements were observed within both groups across all measured outcomes, including increased exercise capacity, better functional independence, and reduced blood pressure and dyspnea levels. However, no statistically significant difference was found between the two groups, indicating that while both exercise regimens are beneficial, the combined approach did not yield superior results within the study's timeframe. The research highlights the value of structured exercise in improving cardiovascular and functional outcomes in NIDCM patients and recommends longer, more varied studies to further explore these benefits.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Both male and female Age 40 to 60
- •Left ventricular ejection fraction <50%
排除标准
- •Patients diagnosed with valvular heart disease, supraventricular arrhythmias, congenital heart disease were excluded.
- •Neuromuscular diseases such as stroke, Parkinson.
- •Underlying pulmonary disease
- •Impaired cognitive function (14)
研究组 & 干预措施
Combined Aerobic and Resistance Exercise:
Participants performed aerobic training three times a week for six weeks.
Each session included a 10-minute warm-up, 30-minute main aerobic activity (60-85% of heart rate reserve using the Karvonen formula), and 10-minute cool-down.
Additionally, they performed resistance exercises for upper and lower extremities using TheraBands, 8-10 sets covering major muscle groups, three times a week.
干预措施: Combined Aerobic and Resistance Exercise (Behavioral)
Combined Aerobic and Resistance Exercise:
Participants performed aerobic training three times a week for six weeks.
Each session included a 10-minute warm-up, 30-minute main aerobic activity (60-85% of heart rate reserve using the Karvonen formula), and 10-minute cool-down.
Additionally, they performed resistance exercises for upper and lower extremities using TheraBands, 8-10 sets covering major muscle groups, three times a week.
干预措施: Aerobic Exercise Only (Behavioral)
Aerobic Exercise Only
Participants followed the same aerobic training protocol as Group A.
No resistance training was included.
Sessions also occurred three times a week for six weeks, with similar warm-up, active, and cool-down phases.
干预措施: Aerobic Exercise Only (Behavioral)
结局指标
主要结局
Functional Independence Measure (FIM) questionnaire
时间窗: Baseline and 6 weeks
Assesses level of functional independence across self-care, mobility, communication, and social cognition.
VO₂ Max (Maximum Oxygen Consumption)
时间窗: Baseline and 6 weeks.
Measured using Graded Exercise Test (GXT) to assess cardiovascular fitness.
Functional Independence Measure (FIM) questionnaire
时间窗: Baseline and 6 weeks
Assesses level of functional independence across self-care, mobility, communication, and social cognition.
VO₂ Max (Maximum Oxygen Consumption)
时间窗: Baseline and 6 weeks.
Measured using Graded Exercise Test (GXT) to assess cardiovascular fitness.
次要结局
- Modified Borg Dyspnea Scale(Baseline and 6 weeks.)
- Blood Pressure (Systolic and Diastolic)(Baseline and 6 weeks.)
- Modified Borg Dyspnea Scale(Baseline and 6 weeks.)
- Blood Pressure (Systolic and Diastolic)(Baseline and 6 weeks.)