NCT06505655尚未招募不适用
Early Diagnosis of Acute Renal Failure, Which May Occur in Patients After Surgeries Requiring Hypotensive Anesthesia, by Urine Trehalase Levels.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- trehalase levels
研究概览
简要总结
We think that in surgical patients requiring hypotensive anesthesia, acute kidney injury, which may occur due to intraoperative renal hypoperfusion, can be diagnosed early by evaluating the urine trehalase value using the ELISA method, and thus, early diagnosed acute renal failure can be treated quickly and patients can be protected from subsequent complications in the postoperative period.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Being over the age of 18 and under the age of 65
- •Having signed the BGOF form to be included in the study,
- •Being in ASA 1 or ASA 2 classification
- •Not having kidney failure or kidney disease
- •No history of single kidney or renal transplantation
- •Not using nephrotoxic drugs or agents before surgery
- •Renal function tests taken preoperatively should be within normal ranges.
- •No urinary tract infection or urinary problems (such as polyuria, oliguria or anuria)
排除标准
- •Those under the age of 18 or over the age of 65
- •Those who do not want to participate in the study
- •ASA 3 and above
- •Having previously received treatment for kidney disease - including kidney stones -
- •Having been previously diagnosed with acute or chronic renal failure
- •Having a single kidney or a history of renal transplantation
- •Using nephrotoxic drugs or agents (such as contrast material) before surgery
- •Kidney function tests taken preoperatively are not within normal ranges
- •Having a urinary tract infection or urinary problem (such as polyuria, oliguria or anuria)
- •Having a history of kidney stones, acute renal failure or chronic renal failure
- •Those with active infection or disease before surgery
- •They were determined as patients for whom consent was not obtained for the study.
结局指标
主要结局
trehalase levels
时间窗: 1 month
urine trehalase levels
次要结局
未报告次要终点
研究者
İlke Dolgun
Assoc. prof
Istinye University
研究点 (1)
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