跳至主要内容
临床试验/NCT03031002
NCT03031002已完成不适用

Extinction Generalization in Exposure Therapy for Spider Phobia

Ruhr University of Bochum0 个研究点目标入组 77 人开始时间: 2015年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
77
主要终点
Change in the Behavioral Approach Test (BAT) from pre- to posttreatment

研究概览

简要总结

Patients with anxiety disorders oftentimes express fear responses to more than only one fear-inducing object. The principal aim of this study is to examine whether the beneficial effects of exposure on fear reduction in spider phobia can extend to stimuli which are conceptually similar to spiders (i.e. cockroaches), but have never been presented during the respective treatment.

详细描述

Fear extinction has evolved as the central mechanism underlying exposure-based treatments. Findings from conditioning studies indicate that fear reduction following a fear extinction procedure can generalize from the extinction stimulus to other conceptually and perceptually related stimuli. This study is aimed at translating these findings to a clinical application and will hence examine whether the basic principles of extinction generalization are applicable to exposure.

Patients with spider phobia will either receive two sessions of in-vivo exposure with spiders or no treatment. Prior to as well as after treatment, patient's fear of spiders will be assessed using the Behavioral Approach Test (BATs) and self-report questionnaires. In addition, BATs with cockroaches will be conducted to examine the effects of exposure therapy on extinction generalization.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • spider phobia according to Diagnostic and Statistical Manual of Mental Disorders (DSM) -IV criteria

排除标准

  • any neurological or neuropsychiatric condition
  • current behavioral or pharmacological treatment
  • any mental disorder that is considered more severe than specific phobia

结局指标

主要结局

Change in the Behavioral Approach Test (BAT) from pre- to posttreatment

时间窗: Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment)

Behavioral Approach Tests with Spiders and Cockroaches will be conducted at pre- and posttreatment. Here, the closest proximity a participant is able to attain to the spider/cockroach will be measured.

次要结局

  • Change in Heart Rate during the Behavioral Approach Tests (BATs) from pre- to posttreatment(Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment))
  • Change in the Spider Phobia Questionnaire (SPQ)(Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment))
  • Change in the Spider Beliefs Questionnaire (SBQ)(Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment))
  • Change in the Fear of Spiders Questionnaire (FSQ)(Pre- and Posttreatment (with approximately 4 days between pre- and posttreatment))
  • Change in Subjective Fear / Disgust during the Behavioral Approach Tests (BATs) using the Subjective Units of Distress Scale (SUDS)(Pre-and Posttreatment (with approximately 4 days between pre- and posttreatment))

研究者

发起方
Ruhr University of Bochum
申办方类型
Other
责任方
Principal Investigator
主要研究者

Armin Zlomuzica

Dr.

Ruhr University of Bochum

相似试验

Extinction Generalization in Exposure Therapy | 临床试验