The Effects of Concurrent Aerobic and Resistance Training on Body Composition and Metabolic Parameters in Women Following Sleeve Gastrectomy: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Change in Body Mass Index (BMI)
研究概览
简要总结
The purpose of this study is to evaluate the effects of a 12-week exercise program on body composition and various physical and physiological parameters in patients who have undergone bariatric surgery. The exercise interventions include aerobic training and combined aerobic and resistance (strength) training. The study aims to determine the impact of these exercise approaches on post-operative recovery and overall physical fitness in this population.
详细描述
Objectives and Methods: This study aimed to investigate the effects of a 12-week structured exercise program on body composition and selected physical and physiological parameters in female patients who had undergone bariatric surgery. A total of twenty women who had received sleeve gastrectomy and were in the early post-operative period (third month after surgery) were included in the study. Participants engaged in supervised exercise interventions consisting of aerobic training as well as combined aerobic and resistance (strength) training protocols, designed in accordance with standard exercise prescription principles. The exercise programs were implemented over a 12-week period with regular monitoring to ensure adherence and safety. Anthropometric measurements, including body weight, body mass index, and waist-to-hip ratio, were obtained using standardized procedures. Body composition parameters such as body fat percentage, regional fat distribution, lean body mass, and basal metabolic rate were assessed using appropriate measurement techniques. In addition, selected biochemical parameters, including markers related to metabolic health, were evaluated through blood analyses. All measurements were conducted at baseline and repeated at the end of the 12-week intervention period under consistent conditions to ensure reliability and comparability of the data.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age between 18-65 years
- •Sleeve gastrectomy performed at least 3 months prior to enrollment
- •Medical clearance for participation in exercise
- •No history of lower extremity injury within the past year
- •Ability to perform cycling and running exercises
排除标准
- •Medical contraindications to exercise participation
- •Surgery performed more than 1 year prior to enrollment
- •Presence of neurological, hormonal, cardiovascular, or respiratory disorders within the past year
- •Lower extremity muscle or joint discomfort within the past 6 months
- •Voluntary withdrawal from the study
- •Occurrence of adverse events during the study
- •Failure to attend ≥2 consecutive sessions per week or ≥20% of total sessions during the 12-week intervention period
- •Exclusion due to non-adherence to the protocol (n=2), resulting in a final sample of 18 participants
研究组 & 干预措施
Aerobic Training Group
Participants in this group perform 12 weeks of structured aerobic exercise for 3 sessions per week. Each session lasts approximately 45-60 minutes at a moderate intensity.
干预措施: Aerobicexercise (Behavioral)
Combined Training Group
Participants in this group perform 12 weeks of combined aerobic and resistance (strength) training for 3 sessions per week. The program includes both moderate-intensity aerobic exercise and resistance exercises targeting major muscle groups (2-3 sets of 8-12 repetitions).
干预措施: Aerobicexercise (Behavioral)
Combined Training Group
Participants in this group perform 12 weeks of combined aerobic and resistance (strength) training for 3 sessions per week. The program includes both moderate-intensity aerobic exercise and resistance exercises targeting major muscle groups (2-3 sets of 8-12 repetitions).
干预措施: Resistance Training (Behavioral)
结局指标
主要结局
Change in Body Mass Index (BMI)
时间窗: Baseline and 12 weeks
BMI is calculated as weight in kilograms divided by the square of height in meters (kg/m2). It is used to assess the change in body mass relative to height following the 12-week exercise intervention.
Change in Body Lean Mass
时间窗: Baseline and 12 weeks
Total body lean mass (fat-free mass) measured in kilograms (kg) using Bioelectrical Impedance Analysis (BIA). This measure assesses the preservation of muscle tissue during weight loss following the 12-week exercise intervention.
Change in Total Body Water
时间窗: Baseline and 12 weeks
Total amount of water in the body, measured in kilograms ($kg$) using Bioelectrical Impedance Analysis (BIA). It reflects changes in hydration status and lean tissue composition.
Change in Basal Metabolic Rate (BMR)
时间窗: Baseline and 12 weeks
The amount of energy expended daily by the body at rest, measured in kilocalories (kcal) via BIA. This measure evaluates the metabolic efficiency following the intervention.
Change in Metabolic Age
时间窗: Baseline and 12 weeks
A calculated value based on BIA parameters that compares an individual's BMR to the average BMR of their age group, measured in years (years).
Change in Glycated Hemoglobin (HbA1c)
时间窗: Baseline and 12 weeks
Measurement of average blood glucose levels over the past 2-3 months, recorded as a percentage (%). Venous blood samples are analyzed to evaluate long-term glycemic control.
Change in Serum C-Peptide Levels
时间窗: Baseline and 12 weeks
Measurement of C-peptide levels in the blood (ng/mL) as an indicator of endogenous insulin production and pancreatic beta-cell function.
Change in Serum Uric Acid
时间窗: Baseline and 12 weeks
Measurement of uric acid concentration in the blood (mg/dL), used to monitor metabolic health and risk of hyperuricemia post-surgery.
Change in Blood Urea Levels
时间窗: Baseline and 12 weeks
Measurement of urea concentration in the blood ($mg/dL$) to evaluate kidney function and protein metabolism during the intervention period.
次要结局
未报告次要终点