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临床试验/NCT04862208
NCT04862208已完成不适用

Comparison of Fasted vs. Carbohydrate and Protein Breakfast on Exercise Metabolism and Rest of the Day Energy Intake

Ohio University2 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2021年5月6日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
2
主要终点
Change in energy expenditure

研究概览

简要总结

Exercising in the fasted state results in greater fat oxidation during exercise and results in decreased caloric intake in the meals after exercise. However, the studies that examine fasted vs. fed exercise utilize a carbohydrate-based breakfast, which can increase blood glucose and insulin concentrations, which is considered a negative consequence. A protein breakfast, which can increase satiety and rest of day energy intake could also increase resting energy expenditure as well as fat oxidation during exercise. However, comparisons between fasting exercise and pre-exercise breakfast macronutrient intake (i.e., carbohydrate vs. protein) have not been made. Therefore the purpose of this study is to investigate if eating breakfast and the composition of this breakfast before exercise has an effect on the food eaten throughout the rest of the day.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • 18-45 years old
  • regularly participate in exercise for at least 150 min per week
  • run at least 3 days per week for 30 minutes
  • able to complete a VO2max test
  • able to exercise for 45 min moderate intensity exercise at one time without breaks

排除标准

  • not participating in structured exercise of 150 min/week for the past 6 months
  • not running at least 3 days per week for 30 minutes
  • not attaining a VO2max of 50 ml/kg/min (60th percentile fitness classification according to the American College of Sports Medicine)
  • currently smoke or quit smoking less than one year ago.
  • diagnosed with or are being treated for a cardiovascular disease, high blood pressure, fibromyalgia, irritable bowel syndrome or a metabolic disorder such as diabetes, thyroid disorder, or high cholesterol.
  • food allergies or sensitivities.
  • not willing to have blood drawn on 4 occasions during each trial (16 total times)

结局指标

主要结局

Change in energy expenditure

时间窗: immediately pre-breakfast, immediately post-breakfast, immediately pre-exercise, and immediately post-exercise

Measured via indirect calorimetry

Change in lunch energy intake

时间窗: 60 min post-exercise

measured via standardized lunch buffet

Change in subjective hunger

时间窗: baseline, immediately pre-breakfast, immediately post-breakfast, immediately post-exercise, immediately pre-lunch, immediately post-lunch, immediately pre-dinner, and immediately post-dinner

measured via 100mm visual analogue scale, higher scores indicate greater hunger

Change in appetite

时间窗: immediately pre-breakfast, immediately post-breakfast, immediately post-exercise, and immediately pre-lunch

measured via circulating hormones

Change in blood glucose

时间窗: immediately pre-breakfast, immediately post-breakfast, immediately post-exercise, immediately pre-lunch, and immediately pre-dinner

measured via fingerstick blood assessment

Change in dinner energy intake

时间窗: Day 1 (trial 1); between Days 6 and 8 (trial 2); between Days 11 and 15 (trial 3); and between Days 16 and 22 (trial 4)

weight of food returned the following day

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Angela Hillman

Assistant Professor, Exercise Physiology

Ohio University

研究点 (2)

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