Prediction of Oculocardiac Reflex in Relationship to Autonomic Nervous System Activity, Mesured With the Use of ECG HRV Analysis.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- oculocardiac reflex occurence in relation to autonomic system activity
研究概览
简要总结
Pulling the eyeball during ophthalmic surgery provokes decrease in heart rate. This phenomenon is called oculocardiac reflex. In some patients asystole may occur. Other cardiac features of this reflex include hypotension, dysrhythmias, atrioventricular block. These cardiovascular disturbances may lead to decreased perfusion and ischemia of vital organs. Patients with existing cardiovascular disease are in risk of complications. Cardiovascular system is mainly innervated with autonomic nervous system (ANS). Sympathetic/parasympathetic activity may be determined by Heart Rate Variability (HRV). HRV analysis based on short 5 minutes electrocardiography has been found useful for prediction of hypotension and bradycardia during induction of general anaesthesia and during spinal block. The aim of this study is to verify whether it is possible to predict oculocardiac reflex with the use of HRV analysis for ANS activity assessment, measured prior to the ophthalmic surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •planned surgery
- •over 18 years of age
- •surgery under general anaesthesia
排除标准
- •urgent surgery
- •under 18 years of age and over 65
- •patients with generalised, nontreated disease
- •patients receiving beta blockers or calcium channel blocker
- •diabetic patients
- •patients operated under peri or retrobulbar anaesthesia
结局指标
主要结局
oculocardiac reflex occurence in relation to autonomic system activity
时间窗: perioperatively - about 2 hours
次要结局
未报告次要终点
研究者
Magdalena Wujtewicz
assistant professor
Medical University of Gdansk
