NCT00805181已完成不适用
Kinetics of Procalcitonin, C-reactive Protein and Pyuria in Uncomplicated Pyelonephritis in Women: A Pilot Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Blood and urine biomarkers (procalcitonin, C-reactive protein, SIGNATURE(TM) test, pyuria
研究概览
简要总结
The objective of this study is to explore the kinetics of biomarkers in 30 adult female patients with uncomplicated acute pyelonephritis.
详细描述
We will measure c-reactive protein, procalcitonin, pyuria and a new blood biomarker (Signature TM) everyday till normalization of these markers in 30 adult female patients with uncomplicated acute pyelonephritis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •> 18 years
- •Flank/loin pain or tenderness, or both and fever > 38°C during the last 48 hours and pyuria
排除标准
- •Pregnancy
- •Presence of indwelling catheters
- •Known polycystic kidney disease or any malformation of the urinary tract, or single kidney; renal transplant recipients; acute or chronic renal failure requiring dialysis
- •Recent discharge from hospital (during the last 10 days); ongoing antibiotic treatment
- •Known severe immunosuppression: Receiver of solid-organ or hematopoietic stem cells transplants; neutropenia ( < 1 G neutrophils / L); chronic (more than 14 days) use of systemic glucocorticoids (>10 mg/d of prednisone); active use of immunosuppressive therapy for the treatment of auto-immune or inflammatory disease; HIV infection with < 350 CD4+ cells / ml or unknown CD4+ status
- •Pyelonephritis initially identified as complicated: obstruction of urinary tract, urinary stone; history of renal infection in the last 15 days
- •Patient with severe sepsis or septic shock
结局指标
主要结局
Blood and urine biomarkers (procalcitonin, C-reactive protein, SIGNATURE(TM) test, pyuria
时间窗: Daily till day 15.
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
撤回
不适用
Procalcitonin Versus C-reactive Protein to Guide Therapy in Community Acquired PneumoniaCommunity-acquired PneumoniaNCT01018199Federal University of Minas Gerais
已完成
不适用
Predictive Value of Procalcitonin, CRP, Drain Fluid Culture, Il-6 and Tnf-α in Anastomotic LeakageAnastomotic Leakage in Colon SurgeryNCT02361918Istanbul University50
已完成
不适用
BIOmarkers of Dyspnea IN Emergency RoomSevere DyspneaCAPDAE COPDAcute Heart FailurePulmonary EmbolismNCT01227317ThermoFisher Scientific Brahms Biomarkers France444
已完成
不适用
Procalcitonin Use in Pneumonia Patients in the Critical Care SettingPneumoniaNCT01788488Mayo Clinic134
招募中
不适用
Evaluating the role of serum procalcitonin and c-reactive protein as a marker for serious infection in young childreCTRI/2012/05/002633MAX SUPER SPECIALITY HOSPITA40