Comparative study of topical minoxidil versus topical minoxidil with dutasteride mesotherapy in androgenetic alopecia A one year hospital based randomized control trial at tertiary care hospital
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 76
- 试验地点
- 1
- 主要终点
- Increased hair density observed trichoscopically
研究概览
简要总结
Although Androgenetic alopecia is often regarded as a rather minor dermatological condition, it affects one’s self-esteem and can be a major source of anxiety and depression for some men.Even while practicing dermatologists and hair specialists deal with it frequently, it might be one of the most difficult conditions to cure because choosing a course of therapy frequently requires careful evaluation of many different aspects as well as ethical decisionâ€making. The most crucial elements to take into account are treatment cost, practicality in terms of promoting compliance, side effect profiles, and effectiveness—especially in light of the chronic nature of the disease.
While hair transplant surgery is an expensive alternative that may not always provide good results requiring numerous procedures to obtain the necessary hair density, medical treatment for AGA may not be suited for all people and may take a long time to show benefits. Therefore, if mesotherapy with dutasteride turns out to be as effective and safe as the current treatment, it might be a tempting substitute.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)(—)
- 性别
- Male
入选标准
- •Patient with Androgenetic Alopecia confirmed by clinical correlation and trichoscopy.
- •Male Patients belonging to age group of 18-55 years.
- •Patients of Norwood classification grading III,IV,V.
- •Patients with no known comorbidites.
排除标准
- •Norwood classification grading III, VI, VII.
- •Patients with other forms of alopecia Patients with dermatological or systemic illness known to cause diffuse hair loss Patients who received PRP or any hair growth promoters in the past six months Patients who underwent surgical hair transplantation.
- •Patients on hormonal, androgenic or anti androgenic medications, cytotoxic, and inhibitors of CYP3A4 Patients suffering from decreased libido, ejaculatory or erectile dysfunction.
结局指标
主要结局
Increased hair density observed trichoscopically
时间窗: 4 months
次要结局
- Reduced inter follicular distance observed trichoscopically(4 months)
研究者
Dr Meenal Agrawal
Jawaharlal Nehru medical college,KLE university
