Effects of Acute Sugar Intake on Choroidal Thickness
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 47
- 试验地点
- 1
- 主要终点
- Change in choroidal thickness
研究概览
简要总结
This study aims to bridge that gap by investigating how acute sugar intake influences choroidal thickness.
详细描述
This investigation will be a prospective, repeated-measures study. All subjects will arrive fasted and will be asked not to consume any outside food or beverages during the three-hour study period, and will be asked to abstain from caffeine intake for 12 hours before participation. A baseline OCT scan of the macula of the right eye will be performed using the Heidelberg Spectralis OCT system. Participants will then consume 30 grams of sugar in the form of glucose tablets. Macular OCT scans of the right eye will be repeated every 30 minutes for 3 hours following sugar consumption.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •In order to be eligible for enrolment, each subject must have less than 6 diopters of spherical equivalent refractive error, and have no existing diagnosis of diabetes or pre-diabetes.
排除标准
- •Any potential subject with known retinal pathology will be excluded. Any potential subject with any other known systemic or ocular conditions that may impact their ability to participate in the study or provide generalizable data will also be excluded.
研究组 & 干预措施
Oral glucose
Subjects receive 30g of oral glucose
干预措施: Oral glucose (Dietary Supplement)
结局指标
主要结局
Change in choroidal thickness
时间窗: within 3 hours of baseline
The primary outcome for this investigation will be changes in choroidal thickness from baseline across timepoints.
次要结局
未报告次要终点