Perioperative Heart Rate Variability Analysis in Realtime: Detection of Cardiovascular and Autonomic Dysfunction
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 88
- 试验地点
- 1
- 主要终点
- Heart rate variability
研究概览
简要总结
This study will record patient electrocardiograms - as well as various other body signals (e.g., blood pressure, pulse wave, peripheral hemoglobin oxygen saturation) - as monitored routinely both during and immediately subsequent to surgical operations performed under general anesthesia. Through retrospective analysis of patients' heart rate variability (HRV), in concert with the other abovementioned parameters, the investigators seek to forward the development of novel mathematical models and tools for on-line detection of cardiovascular and autonomic dysfunction in the perioperative setting.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing non-cardiac surgery under general anesthesia
- •Patients aged 18-80 years
- •Patients who are capable of giving informed consent
排除标准
- •Patients <18 or >80 years of age
- •Patients with an active cardiac pace maker
- •Patients with an absent sinus rhythm in ECG
- •Patients presenting with a preexisting arrhythmia
- •Patients requiring postoperative ICU therapy
- •Patients with pheochromocytoma
结局指标
主要结局
Heart rate variability
时间窗: During and immediately subsequent to surgery performed under general anesthesia
The analysis of heart rate variability (HRV) has been used to assess autonomic nervous system responses to therapeutic interventions, and to quantify risk in a wide variety of both cardiac and non-cardiac disorders when combined with other diagnostic tests - though HRV analysis has seen its greatest cardiologic use in post-myocardial infarction risk stratification and in assessing risk for arrhythmic events. HRV analysis has become widespread and relatively simple to perform - however, until now, these analyses have not been performed in detail in the perioperative period.
次要结局
未报告次要终点
研究者
Adam Joel Bukaty
Dr. Adam Joel Bukaty
Medical University of Vienna