Population pharmacokinetic and pharmacodynamic modeling of gabapentin in neuropathic pain - Effect of adjuvant pharmacotherapy

ppsala University0 个研究点开始时间: 2009年5月14日最近更新: 2012年6月12日

试验速览

暂无简介。

•- Diagnosis of post-traumatic neuropathic pain
•- Spontaneous pain intensity =40 on a 0-100 mm Visual Analogue Scale (VAS) or =4 on a Numerical Rating Scale (NRS)
•- Man or woman =18 years old
•- Informed consent to study participation
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•- Presence of other type of pain as strong as or stronger than the neuropathic pain
•- Impaired kidney function (GFR <30 ml/min)
•- Uncontrolled cardiovascular disease/hypertonia
•- Uncontrolled narrow-angle glaucoma
•- Uncontrolled pulmonary disease
•- Epilepsia
•- Pregnancy
•- Woman of childbearing potential not using contraception or planning to become pregnant during the study period
•- Disability to understand and cooperate with study procedures
•- Allergy to study medications
•- Concomitant participation in other clinical study

发起方

ppsala University