NCT02253329已完成不适用
The Effect of Neuromuscular Electrical Stimulation on Post-prandial Protein Accretion During the Day and Prior to Sleep
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Incorporation of stable isotope amino acids into skeletal muscle tissue
研究概览
简要总结
In the present study, the effect of a bolus of intrinsically labeled milk directly after one-legged NMES (Neuromuscular Electrical Stimulation) will be studied under two conditions: during the day and prior to sleep
详细描述
In the present study, the effect of a bolus of intrinsically labeled milk directly after an hour of one-legged NMES (Neuromuscular Electrical Stimulation) will be studied under two conditions: during the day and immediately prior to sleep
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 85 Years（Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Age 65-85 years
- •18.5 ≤ BMI ≤ 30.0
排除标准
- •Type II diabetes
- •All co morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. arthrosis, arthritis, spasticity/rigidity, all neurological disorders, paralysis, hip/knee surgery).
- •Use of anticoagulants, blood diseases, allergy for lidocaine
- •Use of NSAIDs (non-steroidal anti-inflammatory drugs) and acetylsalicylic acid
- •Patients suffering from PKU (Phenylketonuria)
- •Presence of implantable cardioverter defibrillator and/or pacemaker
- •Performed regular resistance type exercise in the past 6 months
- •Use of any tools to assist during walking (cane/ crutches/ walker)
- •(Partial) foot/ leg amputation
结局指标
主要结局
Incorporation of stable isotope amino acids into skeletal muscle tissue
时间窗: 4-8 hours in the postprandial phase
次要结局
- Plasma amino acid enrichment(4-8 hours in the postprandial phase)
研究者
研究点 (1)
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