An Exercise Intervention Study In NAFLD Patients - CRISTINA

Academisch Medisch Centrum0 个研究点目标入组 30 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

暂无简介。

•- Diagnosis of steatosis on transient elastography, conventional ultrasound,
•magnetic resonance imaging, computed tomography , or by liver biopsy, or
•identified as steatotic subject by fatty liver index (FLI) algorithm which is
•based on waist circumference, body mass index, and levels of triglyceride and γ-
•glutamyltransferase.
•- 18-70 years of age
•- BMI < 40 kg/m2

•- Acute illness or current evidence of acute or chronic inflammatory or
•infective diseases
•- Abusive alcohol use (> 21 IU/week for men, > 14 IU/week for women)
•- Diagnosed liver cirrhosis and/or hepatocellular carcinoma
•- Diagnosed cardiorespiratory, neurological or musculoskeletal disease
•- Diagnosed insulin or GLP-1 agonist treated type 2 diabetes or type 1 diabetes
•- Hepatitis B and/or C or auto-immune hepatitis
•- Wilsons disease/ alpha-1-antitripsine deficiency
•- Hemochromatosis
•- Untreated hypothyroidism
•- Lipoatrophy
•- Bleeding disorder or anti-coagulant use which cannot be temporarily
•discontinued
•- Not able or willing to undergo MRI (for example claustrophobia, ICD,
•- Diagnosed depression or any mental illness rendering the patients unable to
•understand the nature, scope and possible sequences of the study
•- Any participation in regular exercise and/or diet program more than 2 times
•per week in the 3 months prior to recruitment

发起方