Autologous Chondrocyte Transplantation/Implantation Versus Existing treatments: a randomised controlled trial

Keele University (UK)0 个研究点目标入组 400 人开始时间: 2001年5月18日最近更新: 2016年10月17日

试验速览

暂无简介。

•Current inclusion criteria as of 09/11/2012:
•1. Symptomatic chondral defect(s) on the medical or lateral femoral condyle, trochlea or patella suitable for either ACT or one of the existing conventional treatments (debridement, abrasion, drilling, microfracture, mosaicplasty)
•2. Surgical treatment for the same defect carried out at least 12 months previously, that has not relieved symptoms
•3. Not more than two defects, not kissing and total area not greater than 12cm2
•4. Likely to comply with appropriate physiotherapy
•Previous inclusion criteria until 09/11/2012:
•1. Symptomatic chondral defect(s) on the medical or lateral femoral condyle or trochlea suitable for either ACT or one of the existing conventional treatments (debridement, abrasion, drilling, microfracture, mosaicplasty)
•2. Surgical treatment for the same defect carried out at least 12 months previously, that has not relieved symptoms
•3. Not more than two defects, not kissing and total area not greater than 12cm2
•4. Likely to comply with appropriate physiotherapy

•1. Concurrent meniscectomy/osteotomy or untreated malalignment of patella
•2. Generalised osteoarthritis, inflammatory condition or history of mesenchymal tumors
•3. Patient in different clinical trial involving the knee, currently or in last 6 months

发起方

Keele University (UK)