跳至主要内容
临床试验/NCT01136343
NCT01136343已完成不适用

Comparison of Predictive Factors Related to Coronary Artery Disease Among Different Menopausal Status and Effect of a Life Style Management Program on Risk Factors Modification Among Middle-aged Women

Taipei Medical University WanFang Hospital1 个研究点 分布在 1 个国家目标入组 130 人开始时间: 2010年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
130
试验地点
1
主要终点
lifestyle

研究概览

简要总结

In Taiwan, heart disease and cerebrovascular disease ranked the second and third of ten leading causes of death in female in 2007; half of these deaths is due to coronary artery disease (CAD). Postmenopausal status is an independent risk factor for CAD. Early assessment and proper management of risk factors may reduce the prevalence rate of CAD. In the past decade, despite increased attention to CAD in women, most studies focused on certain menopausal status instead of all phases of menopause or on risk factors limited to related metabolic syndrome. Because the prevalence of risk factors related to CAD is influenced by various physiological and lifestyle status in different menopausal statuses, the purpose of this study, at the first stage, is to explore respectively the risk factors of CAD among middle-aged women in three menopausal statuses. At the second stage, the influence of a lifestyle management program on risk factors modification among pre-menopausal women is examined in this study.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
40 Years 至 64 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • diagnosis of CAD by coroangiography
  • LVEF >30%

排除标准

  • impairment of physical activity
  • history of psychiatric disorder, vital arrhythmia

结局指标

主要结局

lifestyle

physical activity, dietary, depression, anxiety

次要结局

  • biomarkers
  • metabolic(6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Chii Jeng

Taipei Medical University

Taipei Medical University WanFang Hospital

研究点 (1)

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