DRKS00006272已完成未知
Changes of the mRNA and microRNA expression profile of individuals with metabolic syndrome after lifestyle-induced weight loss - DIABOWLT (DIABetes Obesity Weight Loss Trial)
Institut für Klinische Chemie und Pathobiochemie Otto-von-Guericke Universität Magdeburg0 个研究点目标入组 74 人开始时间: 2014年7月7日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 74
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 40 Years 至 55 Years（—）
- 性别
- Male
入选标准
- •1. metabolic syndrome with abdominal obesity (waist circumference > 102 cm)
- •2. meet two additional criteria for metabolic syndrome as defined by national Cholesterol Education Program Adult Treatmen Panel III guideliens:
- •- fasting TG conc. > 150 mg/dl
- •- HDL-C < 40 mg/dl
- •- fasting glucose > 110 mg/dl
- •- high blood pressure >140 mmHg systolic and /or > 90 mmHg diastolic or current treatment by anti-hypertensive medication
排除标准
- •1. Smoking
- •2. surgical procedure for weight loss within the previous 6 month
- •3. uncontrolled diabetes (HbA1c > 10%)
- •4. severe renal dysfunction (creatinin concentration > 2.0 mg/dl)
- •5. active liver disease
- •6. obesity of known endocrine origin
- •7. significant haematology abnormalities
- •8. not able to walk at least 30 minutes per day
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