NCT05424029招募中不适用
Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 200
- 试验地点
- 13
- 主要终点
- to isolate exosomes from bronchial washings
研究概览
简要总结
The purpose of this study is to find out if fluid rinsed from peoples' airways (bronchial washing samples) during routine surgery to remove (resect) their non-small cell lung cancer (NSCLC) tumors contains enough vesicles to do testing that may help the researchers learn more about their NSCLC.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients ≥ 18 years of age undergoing consideration of surgical resection, including lobar resections, sublobar resections, and pneumonectomies, for primary lung cancer will be eligible.
- •Patients with previously resected disease and/or previous radiation therapy will be considered on a case by case basis.
排除标准
- •Patients with active infection or pneumonia which may impact exosome makeup
- •Additionally, if at the discretion of the operating surgeon, obtaining bronchial washings would lead to undue morbidity, the patient would be excluded and replaced
结局指标
主要结局
to isolate exosomes from bronchial washings
时间窗: day 1
every patient from whom the essential specimens have been acquired will be evaluated to determine if more than 100,000 microvesicles can be isolated for exosome purification
次要结局
未报告次要终点
研究者
研究点 (13)
Loading locations...
相似试验
尚未招募
1 期
Possible treatment of hereditary-hormonal hair loss by particles isolated from stem cells in the laboratoryIRCT20240508061704N2Shiraz University of Medical Sciences5
招募中
不适用
Analysis of extracellular vesicles and circulating microRNAs in remote ischemic preconditioning of coronary artery disease patientsI25.1Atherosclerotic heart diseaseDRKS00009435niversitätsklinikum EssenKlinik für Anästhesiologie und Intensivmedizin100
已完成
3 期
Analysis of extracellular vesicles and circulating microRNAs in remote ischemic preconditioning of coronary artery disease patients dependent on anesthetic regimeI25.1Atherosclerotic heart diseaseDRKS00015682Ruhr-Universität Bochum Marienhospital HerneKlinik für Anästhesiologie, operative Intensivmedizin,Schmerz- und Palliativmedizin65
已完成
不适用
Breath Volatile Organic Compounds Patterns of Lung Transplant Patients With Chronic Lung Allograft DysfunctionChronic Lung Allograft Dysfunction (CLAD)NCT02836938Prof. Dr. Jens Hohlfeld75
已完成
1 期
A Tolerance Clinical Study on Aerosol Inhalation of Mesenchymal Stem Cells Exosomes In Healthy VolunteersHealthyNCT04313647Ruijin Hospital24