A Study on the Effect of Methylphenidate on Creativity of Healthy Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 主要终点
- The Alternate Uses Task
研究概览
简要总结
Creative cognition plays an important role in art, invention and innovation, as well as in everyday life and thus has a significant effect on society as a whole. Research with healthy, normal participants and those with attention deficit hyperactivity disorder indicates a possible inverse relationship between attentional function and creativity. This evidence raises the possibility that Methylphenidate (MPH; Ritalin) could decrease creativity in people using it for cognitive enhancement. However, this question has not been addressed by previous studies. Hence, the present study aims to examine the effect of MPH on creativity in healthy young adults.
详细描述
Background:
The past decade has seen a rise in the use of prescription stimulants not only by ADHD-diagnosed individual but also by normal healthy individuals for cognitive enhancement. This resulted in a corresponding escalation of illicit use, particularly in college students (confirmed by numerous survey results). In light of this trend, an important issue concerning the effect of cognitive enhancement on the way people think, or what could be called "cognitive style", was raised. Specifically, there has been concern that stimulants might decrease creativity in people using the drugs for cognitive enhancement(.
Creativity has been defined as the ability to produce responses which are both novel (i.e., original, rare and unexpected) and suitable (i.e., adaptive and useful according to the task constrains; ). Many models have been suggested to explain creativity. According to the well established twofold model of creativity, the creative process begins with an associative generation of crudely formed ideas, which is followed by an expansion and exploration of these ideas through a process of evaluation . Since creativity plays an important role in producing novel and useful ideas , it was further speculated that in case of cognitive enhancers continues to be more widely practiced and indeed impair creativity, the effect on society as a whole could be grave The question of whether stimulants might decrease creativity is yet to be elucidated, given that most of previous studies focused on ADHD-diagnosed children, with mixed results; While some of them found that stimulants maintained creativity, others reported it actually worsened the scores on tasks assessing creativity.
Moreover, despite the increase in both illicit and prescribed stimulant use by healthy adults (discussed above) the study by Farah et al.(2009), is so far the only published report investigating stimulant effects on creativity among these individuals. The authors examined the effect of Adderall (a mixture of amphetamine salts) upon creativity, in 16 healthy adults on four tests of creativity, "two tasks requiring divergent thought and two requiring convergent thought (p. 542)." Only performance on the convergent tasks was affected, and the effect depended on baseline performance: in one case enhancing it, particularly for lower-performing individuals, and in the other case enhancing it for the lower-performing and impairing it for higher-performing individuals. This pattern of differential effect of stimulants based on baseline performance, has been noted in other studies of stimulants and cognition and is not unique to creative thought.
Hence, the question of whether stimulants might decrease creativity in healthy adults using the drugs for cognitive enhancement is still open. To best of our knowledge, though MPH is a widely used by healthy normal individuals to enhance cognition, its effect upon creativity of healthy adults has not been studied before. We therefore sought to investigate the effect of MPH upon creativity in healthy adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 40 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participants, aged 21-40 years
排除标准
- •People diagnosed with a psychiatric clinical disorder and /or taking psychotropic drugs (whether prescription drugs, herbal extracts or illegal drugs), which may impair their performance in tasks that are used in the study).
- •People for whom there is a contra-indication for consuming Ritalin:
- •People who are or were diagnosed with cardiac medical condition, hypertension, liver damage, glaucoma or neurologic disorders (e.g. epilepsy, CVA, parkinson's, Aneurism, brain SOL, MS).
- •Pregnant or nursing women; female participants will be required to report whether they are pregnant, and in case they are, they will not participate.
- •Reported use of drugs at the previous 30 days.
研究组 & 干预措施
Experimental: Healthy adults
Participants, aged 21-40 years, will be recruited through an advertisement posted at the University of Haifa (including the website of Haifa University).
干预措施: MPH (Drug)
结局指标
主要结局
The Alternate Uses Task
时间窗: 30 min
This is a standard measure of divergent thinking, whose stimuli and responses are verbal. Subjects will be presented with a list of six common objects (shoe , can, stapler, tire, drinking glass, cardboard box) and will be asked to list as many alternate uses as possible for each object, within a ten minute time limit (the most common everyday use is indicated in parenthesis). Fluency, flexibility and originality will be scored. Original responses will be defined as statistically infrequent responses according to a pretest conducted in our lab
次要结局
- Torrance Tests for Creative Thinking (TTCT):(10 min)
- Motivation from having an effect(12 min)
- The Balloon Analogue Risk Task (BART):(10 min)
- The Evaluation Task(10 min)
- Remote Associates Test (RAT)(20 min)
- visual selection and awareness(3 min)
