Will Adjusting the pH of Lidocaine Reduce the Pain During Injection of Local Anaesthetic?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Pain
研究概览
简要总结
This study will investigate the influence of adjusting the pH of lidocaine on pain during subcutaneous injection. Each participant will receive two injections on the abdomen with different pH. After each injection, the subject will be asked to evaluate the pain on a Visual analog scale (0-100 mm). It is anticipated that the pain decreases with increasing pH. The aim of the study is to find a simple method for pain reduction that can be used in clinical practice.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 18-65 years
排除标准
- •Kidney, heart or liver disease
- •Eczema or psoriasis on injection site
- •Neuropathy
- •Regular use of painkillers
- •Hypersensitivity of Lidocaine
- •Pregnancy
研究组 & 干预措施
Bicarbonate
Each participant will receive two lidocaine injections on the abdomen with different pH
干预措施: Lidocaine injection with bicarbonate (Procedure)
Bicarbonate
Each participant will receive two lidocaine injections on the abdomen with different pH
干预措施: lidocaine injection (Procedure)
结局指标
主要结局
Pain
时间窗: 60 seconds
1. Visual Analog Scale 0-100 mm 2. Questionnaire
次要结局
未报告次要终点