Colchicine Has Anti-diabetic Effect and May be an Option for Type 2 Diabetes Management
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- colchicine for treatment of type diabetes patients
研究概览
简要总结
Colchicine has antidiabetic effect and may be an option for type 2 diabetes management
详细描述
Observational cohort prospective study with following of 150 newly diagnosed type 2 diabetes patients who were in 3 groups, had been monitored in a private clinic, each group 50 patients number, with 30 females and 20 males after written consent from all patients. The ages of all patients were between 35 and 55 years.
The aim of this study was to evaluate colchicine effect on A1C of newly diagnosed type2 diabetes compared to the metformin and control group on diet only.
The first group patients received colchicine 0.5twice daily for 6 months, the second group received metformin 1gm twice daily, the third group patients were on diet only. During the period of treatment, the investigators followed the patients if there were side effects of the drugs used. No side effects were monitored during the period of treatment except for gastric upset in some patients using metformin
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 35 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •type 2 diabetes newly diagnosed age 35- 55 years
排除标准
- •severe anemia hypothyroidism and hyperthyroidism moderate to severe liver or kidney disease
研究组 & 干预措施
group 1 on cochicine
The first group patients received colchicine 0.5 twice daily for 6 months
干预措施: Colchicine Tablets (Drug)
group 2 on glucophage 1 gm twice daily
second group received glucophage 1gm twice daily for 6 months
干预措施: Colchicine Tablets (Drug)
group 3 control
the third group patients were on diet only for 6 months
干预措施: Colchicine Tablets (Drug)
结局指标
主要结局
colchicine for treatment of type diabetes patients
时间窗: 6 months
colchicine tablets .5 mg twice daily for 6 months
次要结局
未报告次要终点
研究者
mahmoud younis
consultant
Ministry of Health and Population, Egypt