Boosting Cognitive Reserve Through Adult Second Language Acquisition With Duolingo
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 90
- 试验地点
- 2
- 主要终点
- Change in inhibitory Control, DKEFS
研究概览
简要总结
Bilingualism has been shown to have a strong protective effect against dementia, delaying the diagnosis of Alzheimer's disease by up to 4 years. The purpose of the study is to test whether learning a second language using Duolingo software could improve cognitive functions in older adults.
详细描述
This study is a 3-arm, randomized controlled trial. The primary objective of the study is to test the impact of second language acquisition through short-term use of the Duolingo app on cognitive functioning, particularly executive function in older adults compared to a brain training application.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 75 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participants must have normal vision and hearing.
- •Participants must be able to travel to Baycrest by personal or study-arranged automobile, or public transportation.
- •Participants must be monolingual native English speakers.
- •Participants must be willing to provide informed consent.
- •Participants must have daily access to a smartphone/mobile device.
- •Have not previously studied Spanish formally, nor any other language in the past 10 years.
排除标准
- •have a neurological disorder.
- •meet DSM-IV-TR criteria for Axis I mood, anxiety, or psychotic or substance abuse disorders.
- •Fluent in more than one language.
研究组 & 干预措施
Duolingo Spanish Course
30 minutes each day, 5 days a week for 16 weeks. Total of 40 hours.
干预措施: Duolingo (Behavioral)
BrainHQ
30 minutes each day, 5 days a week for 16 weeks. Total of 40 hours.
干预措施: BrainHQ (Behavioral)
Passive Control
No intervention.
干预措施: Passive Control (Behavioral)
结局指标
主要结局
Change in inhibitory Control, DKEFS
时间窗: change from baseline to 16 weeks
DKEFS Colour Word Interference
Change in inhibitory Control, Simon task
时间窗: change from baseline to 16 weeks
Inhibitory control assessed by the Simon task
Change in working memory, n-back
时间窗: change from baseline to 16 weeks
Working memory assessed by the n-back test
次要结局
- Change in attention abilities(change from baseline to 16 weeks)
- Change in language abilities(change from baseline to 16 weeks)
- change in verbal fluency(change from baseline to 16 weeks)
- executive function assessed by trailmaking test(change from baseline to 16 weeks)
研究者
Jed A. Meltzer, Ph.D
Neurorehabilitation Scientist
Rotman Research Institute at Baycrest