Effects of Low Intensity, High Intensity Eccentric Resistance Training Associated With Blood Flow Restriction: a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 61
- 试验地点
- 2
- 主要终点
- Change in Vascular Endothelial Growth Factor (VEGF)
研究概览
简要总结
Introduction: studies on resistance training of low intensity associated with blood flow restriction in recent years, although there are still gaps that can be explored in relation to their physiological phenomena when associated with eccentric training. In this way, from there the exploration becomes relevant the investigation of eccentric training associated to an RFS. Objective: To analyze and compare the effects of a high intensity and low intensity intensive resistance training associated with an RFS (TREAI-RFS and TREBI-RFS) with a high intensity eccentric resistance training without RFS (TREAI) in knee extensors. Method: The study will consist of 45 male participants, allocated from a stratified randomization into three groups: TREAI (n = 15), TREAI-RFS (n = 15) and TREBI-RFS (n = 15). Participants underwent a training program with a minimum of 40% without RFS, 80% with RFS and 40% with CVS of CVIM, 3 times a week, and the outcomes of muscle strength, muscle structure, power test and Endothelial growth will be assessed one week before, the fourth week and one week after the end of the training program. In addition, clinical markers of perception and recovery effort are investigated before and after a session. The graph used is descriptive and descriptive, as it is used as a model of analysis of variance for the analysis of replications without a two-factor scheme, which provides detailed information on how the measures are repeated, neither. A whole statistical analysis can reach the level of significance of 5%.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •male sex;
- •aged between 18 and 35 years
排除标准
- •alcoholics;
- •use drugs that influenced cardiac autonomic activity;
- •cardiovascular, metabolic or endocrine diseases.
结局指标
主要结局
Change in Vascular Endothelial Growth Factor (VEGF)
时间窗: baseline, fourth week and one week after sixth week.
For the analysis of the concentration of endothelial growth factor (VEGF) will be collected 10 ml of blood sample. The plasma of this sample will be stored at -80 ° C for further analysis.
Change in muscular structure with ultrasonography
时间窗: baseline, fourth week and one week after sixth week.
Ultrasonographic imaging of the dominant lower limb will be captured to determine muscle thickness of the vastus lateralis (VL) and rectus femoris (RF) muscles.
Change in muscle strength torque peaks at dinamometer isokinetic
时间窗: baseline, fourth week and one week after sixth week
The isometric, eccentric and concentric torque peaks will be measured with an isokinetic dynamometer in order to evaluate the adaptations of knee extensor force to eccentric training.
Change in muscle power test
时间窗: baseline, fourth week and one week after sixth week.
The strength and muscle power tests will be performed on a vertical squat with a guided bar.
次要结局
- Perceived Effort Scale (Borg)(Assessed at baseline, 4th week, and 6th week.)
- Analog Visual Scale(Assessed at baseline, 4th week, and 6th week.)
- Recovery Perception Scale(Assessed at baseline, 4th week, and 6th week.)
- Pain threshold(Assessed at baseline, 4th week, and 6th week.)
研究者
Franciele Marques Vanderle
PhD
Paulista University