Projected Influence of Enhanced Pathogen Detection on the Clinical Management of Community-Acquired Pneumonia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 570
- 试验地点
- 1
- 主要终点
- Pathogen Detection
研究概览
简要总结
Study to compare the number of community-acquired pneumonia (CAP) pathogens detected using current diagnostic tests to the number detected using the BioFire Diagnostics investigational polymerase chain reaction (PCR) platform.
详细描述
Patients diagnosed in the emergency department with CAP that requires hospitalization provide a sputum sample for culture and sensitivity testing, urine for detection of S. pneumonia and L. pneumophila, an anterior nasal swab for S. aureus PCR, a nasopharyngeal swab for S. pneumonia PCR and the FilmArray LRTI v.2.0 IUO Panel, and blood for procalcitonin testing and, in cases in which the patient is suffering rigors and hypotension, cultures. As part of this study, sputum or sputum equivalent will be acquired for testing using the FilmArray LRTI v.2.0 IUO Panel.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Emergency Department physician diagnosis of CAP requiring hospitalization
排除标准
- •Inability to obtain sputum or sputum equivalent
研究组 & 干预措施
FilmArray LRTI v.2.0 IUO Panel
Patients will provide sputum or sputum equivalent for FilmArray LRTI v.2.0 IUO Panel testing.
干预措施: FilmArray LRTI v.2.0 IUO Panel (Other)
结局指标
主要结局
Pathogen Detection
时间窗: 5 Days
Compare the number of CAP pathogens detected using current diagnostic bundle to the number detected using the FilmArray LRTI v.2.0 IUO Panel.
次要结局
- Treatment Influence(5 Days)
- Nasopharyngeal swabs compared to sputum(5 Days)