NL-OMON54262招募中不适用
ltra- High field ImaGing in Huntington*s Disease - Ultra-HIGH-D
Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 60 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •General inclusion criterium:
- •- Between 18 years and 75 years of age
- •Inclusion criteria pre-manifest participants:
- •- An UHDRS motor score <= 5
- •- CAG repeat size of 36 or more
- •Inclusion criteria manifest participants:
- •- An UHDRS motor score > 5
- •- Disease Stage 1 or 2
- •- CAG repeat size of 36 or more
- •- TFC between 7 and 13 (disease stage 1 or 2)
- •Inclusion Criteria gene negative controls
- •- a CAG repeat size of 35 or less
排除标准
- •- Subjects with contra-indications for a MRI-scan as defined in the MRI
- •screening form of SCANNEXUS such as claustrophobia, subjects carrying
- •incompatible metallic devices, subjects who have an allergy for intravenous
- •contract or subjects who are pregnant.
- •- Manifest participants who are not capable of consenting
- •- Manifest patients not capable of undergoing MRI because of involuntary
- •- Genotype unknown
- •- Current participation in a drug trial
- •- Not agreeing to be informed about incidental findings on the MRI scan
- •- Known kidney insufficiency
研究者
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