NCT03997929已完成不适用
Prospective Evaluation of 1.3-ß-D-glucan in the Peritoneal Fluid for the Diagnosis of Fungal Peritonitis in Critically Ill Patients
Central Hospital, Nancy, France4 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2020年1月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 4
- 主要终点
- Measure of 1.3 BDG in the peritoneal exudate of patient with intra-abdominal candidiasis
研究概览
简要总结
New rapid diagnostic strategies are warranted in intra-abdominal candidiasis (IAC). A previous retrospective study showed that one measure, the day of the surgery, of peritoneal 1.3-Beta-D-Glucan ≤ 310pg/ml could rule out an IAC. This strategy was independent of the patient underlying conditions and Candida risk factors. This study aimed to confirm these results with a multicenter prospective study
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •critically ill adult (> 18 yrs old) admitted to ICU for intra-abdominal infection requiring surgery and possible intra abdominal candidiasis
排除标准
- •declinate to participate,
- •expected death within the first 24 hours
结局指标
主要结局
Measure of 1.3 BDG in the peritoneal exudate of patient with intra-abdominal candidiasis
时间窗: 1 DAY
Value of 1.3 BDG in the peritoneal exudate in patient with intra-abdominal candidiasis in comparison with non intra-abdominal candidiasis
次要结局
- Measure of 1.3 BDG in the serum of patient with intra-abdominal candidiasis(DAY 1 and DAY 3)
研究者
研究点 (4)
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