An Investigation of the Effects of Consuming Oatcakes Containing 4g of Oat Beta-glucan on Physiological Parameters in Individuals at Risk of Developing Metabolic Syndrome
试验速览
- 阶段
- 不适用
- 入组人数
- 90
- 试验地点
- 2
- 主要终点
- Waist Circumference
研究概览
简要总结
The purpose of this study is to determine whether daily consumption of soluble fibre, oat beta glucan (4g), for six weeks will have any impact on overweight/obese individuals in terms of risk factors used to define metabolic disease.
详细描述
The purpose of this study is to determine whether daily consumption oat beta glucan (4g) for six weeks will have any impact on overweight/obese individuals in terms of risk factors used to define metabolic disease.
Oat beta-glucan has been incorporated into a novel oatcake product manufactured by Nairn's Oatcakes Ltd. Consumption of the oatcake products will deliver enough oat-beta glucan to the diet to meet European Food Safety Authority health claims for lowering blood cholesterol and reducing post-prandial glycaemic responses.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Males and females 18 years and older
- •Waist circumference measurements of ≥94cm for males and 80cm for females, or a body mass index of ≥30kg/m2
- •Individuals who are able to provide informed consent
排除标准
- •Postmenopausal females
- •Individuals who suffer from, or taking medication for, cardiovascular or gastro-intestinal disease
- •Impaired glucose tolerance/Diabetes mellitus
- •Pregnancy or breastfeeding
- •Those who have high dietary fibre intakes (>20g/day)
- •Known food allergies to oats, wheat, lactose, or sesame seeds
结局指标
主要结局
Waist Circumference
时间窗: 6 weeks
次要结局
- Fasting Serum Triglycerides(6 weeks)
- Fasting Serum total Cholesterol(6 weeks)
- Interleukin-6(6 weeks)
- Blood Pressure(6 Weeks)
- Fasting Serum HDL Cholesterol(6 Weeks)
- Oral Glucose Tolerance Test(6 weeks)
- Energy Intakes (kilocalories) and Macronutrient intakes (grams) from food diaries(6 weeks)
研究者
Suzanne Zaremba
PhD Student
Queen Margaret University