BRILMA Block: A Regional Approach to Pain Management in Breast-Conserving Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Morphine consumption
研究概览
简要总结
Regional analgesia technique in addition to multimodal analgesia in breast-conserving surgery aims to reduce opioid consumption. This study evaluates the postoperative analgesic efficacy of ultrasound-guided BRILMA block in patients undergoing breast conserving surgery.
详细描述
Breast-conserving surgery has become a standard surgical approach in the management of early-stage breast malignancies. Despite being less invasive than other oncologic procedures, postoperative pain remains a significant concern. In postoperative pain management, the addition of regional analgesia techniques to multimodal approaches aims to reduce opioid consumption.
First described in 2013, the Serratus-Intercostal Interfascial Plane block targets the branches of the intercostal nerves at the level of the mid-axillary line, specifically around the fourth rib-an anatomical region referred to by the acronym BRILMA. This regional anesthesia technique has demonstrated efficacy in managing postoperative pain, particularly after breast surgery.
In the study, investigators planned to evaluate the postoperative analgesic efficacy of ultrasound-guided BRILMA block via 24-hour morphine consumption in patients undergoing breast conserving surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Breast-conserving surgery
- •ASA I-III
排除标准
- •Patient refusal
- •Presence of contraindications for regional anesthesia ( bleeding disorder, infection at the injection site, local anesthetic allergy)
- •Chronic analgesic use
- •Preoperative breast pain
结局指标
主要结局
Morphine consumption
时间窗: postoperative 24-hour
Amount of morphine consumption
次要结局
- Static and dynamic pain scores assessed with numeric rating scale(postoperative 24 hours)
- number of blocked dermatome(20. minute after block performance)
- Duration of block application(up to 15 minutes)
- Amount of fentanyl for sedation. [Time Frame: Intraoperative 2-3 hours](during surgery)
- Rescue analgesia(postoperative 24 hours)
- Nausea and vomit(postoperative 24 hours)
- Complications(Up to 24 hours)
- Patient's satisfaction(Up to 24 hours)
研究者
Nukhet Sivrikoz
Attending Anesthesiologist
Istanbul University