The Impact of Dry Eye Syndrome on Novel Metrics of Low Contrast Vision Before and After Therapeutic Meibomian Gland Expression
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Change in Response Time on Cone Contrast Test (CCT, Innova Systems, Inc.)
研究概览
简要总结
The study aims to determine the impact of Meibomian Gland Dysfunction (MGD) dry eye on low contrast black/white (luminance) and cone color sensitivity performance and improvement in these functions after in-house non-invasive Meibomian gland (MG) expression.
详细描述
This study offers possible benefits from gland expression to patients and subjects in terms of clinical measurements and care associated with meibomian gland dysfunction impacting all age ranges. Prior studies show that these interventions improve dry eye symptoms with intent to improve vision, low contrast color, and B/W vision after intervention in this study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Individuals over the age of 18 years
- •Healthy individuals with reported symptoms of dry eye such as burning, stinging, fluctuating vision, inappropriate tearing, and feelings of grittiness particularly with prolonged near work
排除标准
- •Under the age of 18
- •Individuals currently using prescription eye medications for dry eye / MGD / inflammation / Infections or any other treatments.
结局指标
主要结局
Change in Response Time on Cone Contrast Test (CCT, Innova Systems, Inc.)
时间窗: This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention.
This computer test measures average response time in seconds to see red, green and blue low contrast letters.
Change in Cone Contrast Sensitivity on the Cone Contrast Test (CCT, Innova Systems, Inc.)
时间窗: This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention.
This computer test measures the lowest contrast (contrast sensitivity) to see red, green and blue cone specific letters.
次要结局
- Change in Visual Acuity Test at Low Contrast (Innova Systems, Inc)(This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention.)
- Change in Response Time on Black White Contrast Sensitivity Test (Innova Systems, Inc) Response Time(This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention.)
- Change in Black White Contrast Sensitivity (Innova Systems, Inc)(This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention.)
- Change in Response Time on Visual Acuity Test at Low Contrast (Innova Systems, Inc)(This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention.)
- Change in Color Naming Accuracy on Cone Contrast Color Naming test (CCNT)(This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention.)
- Change in Sensitivity on Cone Contrast Color Naming test (CCNT)(This test will occur prior to the intervention (Meibomian gland expression) and immediately after this intervention.)
研究者
JEFFREY CARL RABIN
Professor and Assistant Dean for Graduate Studies, Research and Assessment and Chief, Visual Neurophysiology Service
University of the Incarnate Word