Effect of Combined Fatty Acid Supplementation and Eccentric Exercise Training on Exercise Performance, Inflammation, Gene Expression and Epigenetic Signatures
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Strength
研究概览
简要总结
The aim of the study is to determine whether fish oil (specifically omega-3 long chain polyunsaturated fatty acids [EPA-DHA]) supplementation can enhance eccentric resistance exercise performance when combined with a resistance exercise training study. The investigators aim to establish the potential mechanisms that might mediate performance changes at a cellular level.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Resistance exercise training within the past 6 months
- •Vitamin or fish oil supplementation over the past 6 months
- •Habitual use of anti-inflammatory drugs
- •History of heart disease
- •History of coagulation/bleeding disorder
- •History of metabolic disease
- •Serious allergy
- •Known to have blood-borne virus
- •Females (Due to differences in cell membrane incorporation of Omega-3 between the sexes and the testing schedule being unable to fit in with menstrual cycle, altering the blood markers that are being measured)
- •Currently no symptoms of general illness
研究组 & 干预措施
Placebo
Olive Oil 6g/ day - Premium Omega-3, Norwegian Pure-3, Oslo, Norway
干预措施: Placebo (Dietary Supplement)
Fish Oil
Fish oil 5.1g/ day - Premium Omega-3, Norwegian Pure-3, Oslo, Norway
干预措施: Fish Oil (Dietary Supplement)
结局指标
主要结局
Strength
时间窗: Change from baseline strength at 11 weeks
Quadriceps and Hamstring strength using an isokinetic dynamometer
Leg power
时间窗: Change from baseline strength at 11 weeks
Dynamic leg power assessed through jump height on force platform
次要结局
未报告次要终点
研究者
Lynsey Wilson
Technical Tutor in Exercise Physiology/ PhD Student
Loughborough University