Evaluation of the efficacy of a combination of Methylprednisolone and Etoricoxib to attenuate postoperative pain and PONV in patients undergoing laparoscopic surgery
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1. To evaluate the effect on Post operative Pain.
研究概览
简要总结
The aim of the study is to Evaluate the Efficacy of a Combination of Methylprednisolone(125mg IV) And Etoricoxib(120mgORALLY) to Attenuate Postoperative Pain and PONV in Patients Undergoing Laparoscopic Surgery in the terms of:-
PRIMARY OBJECTIVES:
- To evaluate the effect on Post operative Pain.
2 .To evaluate the effect on PONV.
SECONDARY OBJECTIVES:
1.To assess fentanyl dose consumption.
2.To assess duration of analgesia.
3.To assess and compare the quality of Post op analgesia
-
To assess and compare the hemodynamic changes if any.
-
To assess and compare the proportion of patient having adverse
effects and any other complications.
- To evaluate its effects on PONV, fatigue, sedation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Adult patients (20-65 yrs) of either sex 2.ASA physical status I or II 3.Patients scheduled for laparoscopic Surgery under general anaesthesia.
排除标准
- •1.ASA Physical Status III or above 2.Patients with impaired kidney or liver functions, 3.A history of drug or alcohol abuse 4.A history of chronic pain or daily intake of analgesics.
结局指标
主要结局
1. To evaluate the effect on Post operative Pain.
时间窗: 1. To evaluate the effect on Post operative Pain. | 2 .To evaluate the effect on PONV.
2 .To evaluate the effect on PONV.
时间窗: 1. To evaluate the effect on Post operative Pain. | 2 .To evaluate the effect on PONV.
次要结局
- 1.To assess fentanyl dose consumption.(2.To assess duration of analgesia.)