EUCTR2010-019815-40-SE进行中（未招募）不适用
Avastin and chemotherapy followed by a KRAS stratified randomization to maintenance treatment for first line treatment of metastatic colorectal cancer - ACT2
Skåne University Hospital, Department of Oncology0 个研究点目标入组 230 人开始时间: 2010年7月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 230
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •1. Untreated metastatic colorectal carcinoma.
- •2. Age 18 years or more.
- •3. Measurable disease according to Response Evaluation Criteria in Solid Tumors
- •(RECIST) criteria.
- •4. Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1.
- •5. Life expectancy more than 3 months.
- •6. Adequate haematological, renal and liver function.
- •7. Tumor tissue available for determination of KRAS mutational status.
- •8. Blood sample and paraffin embedded tumor tissue for translational research.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 100
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 130
排除标准
- •1. Adjuvant therapy within 6 months.
- •2. Central nervous system (CNS) metastases.
- •3. Clinically significant atherosclerotic vascular disease.
研究者
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