Using the Superb Microvascular Imaging Method in the Diagnosis of Intraocular Tumors (SMITIS)
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 22
- 试验地点
- 2
- 主要终点
- Qualitative description of the intratumoral microvascular flow
研究概览
简要总结
The diagnosis and monitoring of intraocular tumors are based on multimodal imaging in addition to the clinical examination (ultra-widefield retinal imaging, echography, angiography). Nevertheless, it may be difficult in cases of retinal hemorrhage, small tumor size or atypical presentation. The study of microvascular flow (Superb Microvascular Imaging, SMI) of intraocular tumors could improve the confidence of differential diagnosis when evaluating these suspicious lesions, or even determine whether a lesion is benign or malignant by describing the vascularization of the lesion.
The investigators propose to study the microvascular flow patterns of intraocular tumors prior to proton therapy.
详细描述
The ultrasound equipment available in ophthalmology does not have Doppler technology and does not allow the study of the vascularization and microvascularization of intraocular lesions. The interest in the system used in this study is to import SMI into ophthalmology to study tumor microvascularization. The study of tumor vascularization can help in the differential diagnosis and follow-up of tumors, and therefore can impact the management of patients with tumors.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years
- •Intraocular tumor not previously treated with proton therapy
排除标准
- •Severe active ocular, periocular or intraocular inflammation
- •Intraocular pressure > 30 mmHg
结局指标
主要结局
Qualitative description of the intratumoral microvascular flow
时间窗: Month 6
Number of visible feeding pedicles
次要结局
- quantification of microvascular flow for each tumor(month 6)