Pre-operative Ultrasonographic Evaluation of the Internal Jugular Vein Collapsibility Index and Inferior Vena Cava Collapsibility Index to Predict Post Spinal Hypotension in Pregnant Women Undergoing Caesarean Section
试验速览
- 阶段
- 不适用
- 入组人数
- 55
- 主要终点
- pre-operative inferior vena cava collapsibility index (IVCCI)
研究概览
简要总结
Postspinal hypotension (PSH) is common in obstetric anesthesia practice, with an incidence of up to 71 %. PSH can occur precipitously and, if severe, can result in both maternal and fetal/neonatal adverse events. Pregnant women with predelivery hypovolemia are at risk of cardiovascular collapse and the sympathetic blockade may severely decrease venous return. Hence, prevention of PSH is an essential element in obstetric anesthesia and fasting for aspiration prophylaxis may further add up to the hypovolemia for the patients not on maintenance fluids.
Hemodynamic monitoring in obstetric patients has evolved during the last decade, with the development of minimally invasive and noninvasive continuous cardiac output (CO) monitors. Ultrasound (USG) is a method for noninvasive hemodynamic optimization in the ICU and ED, and it may be more helpful than other noninvasive methods. Transabdominal USG measurements of inferior vena cava (IVC) are noninvasive and thus are not associated with complications. USG of the IVC diameter is a useful and easy method for assessing a patient's volume status by calculating the IVC collapsibility index (IVCCI).
Recently, the usefulness of point-of-care ultrasonographic examination, performed by anesthesiologists in real time, for perioperative management has been reported . Ultrasonographic studies have established the utility of measuring the inferior vena cava (IVC) or internal jugular Vein (IJV) for evaluating intravascular volume status .
In particular, IVC diameter and collapsibility, obtained from ultrasonographic measurement, have been demonstrated to be predictors of hypotension after anesthetic administration.
详细描述
Pregnant women planned for elective surgery will be advised for nil per oral after midnight and. After detailed preanesthetic checkup, on arrival in operating room, standard monitoring devices will be attached (pulse oximeter, noninvasive blood pressure and 3-lead electrocardiography).
Machine
A sonosite M-Turbo ultrasound machine will be used for all the examinations. A curvilinear USG probe for IVC imaging (1-5 MHz, 21 mm). A linear vascular transuder for IJV imaging (7-13 MHz, 38 mm) will be used.
Measurements
IJV measurement
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Care Provider)
入排标准
- 年龄范围
- 20 Years 至 40 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •1.55 female patients
- •aged 20-40 years 3.ASA Physical Status Class I and II
- •scheduled for elective lower segment cesarean section
排除标准
- •Patients who will refuse
- •Emergency LSCS
- •Patients with expected massive intraoperative blood loss e.g. placenta Previa and placenta accreta
- •Cardiovascular, respiratory, renal diseases
- •Patients who will receive preloading of intravenous fluid
结局指标
主要结局
pre-operative inferior vena cava collapsibility index (IVCCI)
时间窗: pre-operative
for predicting post-spinal anaesthesia hypotension (PSAH). The maximum (IVCD) and minimum (IVCD) internal anteroposterior (AP) diameters of the IVC at the end of expiration and inspiration respectively over the same respiratory cycle will be measured. The IVCCI is derived from the equation, IVCCI= (IVCD max -IVCD min)/IVCD max × 100
pre-operative internal jugular vein collapsibility index (IJVCI)
时间窗: pre-operative
for predicting post-spinal anaesthesia hypotension (PSAH), The maximum, minimum antero-pestorior diameters, and cross-sectional area will be estimated and, from this, corresponding collapsibility index will be derived (Maximum diameter or cross-sectional area (CSA)-minimum diameter or CSA/maximum diameter or CSA) ×100%.
次要结局
未报告次要终点
研究者
Amr Arafa Elbadry
Principal Investigator
Tanta University
