SAB-Support-Study: Can Checklist-based Phone Calls Improve the Quality of Staphylococcus Aureus Bacteraemia (SAB) Management
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 124
- 试验地点
- 1
- 主要终点
- SOP adherence, calculated as a sum score per patient with the following 8 parameters:
研究概览
简要总结
The main objective of this study is to investigate whether checklist-based close telephone consultation and process surveillance for S. aureus bacteraemia (SAB) can improve adherence to our in-house SAB-guidelines (prospective quality- improvement group).
In addition, the effects of telephone consultation on the clinical outcome of patients will be examined.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥ 18 years
- •Inpatient treatment at the University Medicine Greifswald university hospital
- •First diagnosis of SAB in hospital
排除标准
- •SAB already known before admission
- •Palliative management within 48 hrs after SAB diagnosis
- •Death within 48 hrs after SAB diagnosis
- •Hospital discharge within 48hrs after SAB diagnosis
结局指标
主要结局
SOP adherence, calculated as a sum score per patient with the following 8 parameters:
时间窗: Hospital admission until hospital discharge (no later than day 90 after diagnosis)
1. Drawing of follow-up blood cultures 2-3 days after start of adequate antibiotic therapy 2. Early source control (removal of infected material or drainage of an abscess ≤ 72 hrs) 3. Adequate search for SAB focus and metastatic manifestations 4. TEE in patients with clinical indications (within 4 days of SAB diagnosis) 5. Early start of specific therapy after receipt of results via phone call (≤12 hrs) 6. Adequate dosage of antibiotic 7. Sufficient duration of therapy (at least 14 d for uncomplicated bacteremia and 28 d for complicated bacteremia) 8. Combination therapy with Rifampicin or Fosfomycin, when indicated
次要结局
- Time to specific antimicrobial treatment according to guidelines concerning agent and duration(Hospital admission until hospital discharge (no later than day 90 after diagnosis))
- Time to negativity of follow up blood cultures(Day of SAB diagnosis until hospital discharge (no later than day 90 after diagnosis))
- Time till TEE is performed (when indicated)(Hospital admission until hospital discharge (no later than day 90 after diagnosis))
- Length of hospital stay after SAB diagnosis(Day of SAB diagnosis until hospital discharge (no later than day 90 after diagnosis))
- In-hospital mortality (all patients)(Hospital admission until hospital discharge (no later than day 90 after diagnosis))
- In-hospital mortality (because of SAB complications)(Hospital admission until hospital discharge (no later than day 90 after diagnosis))
- Hospital readmission until day 90 after SAB diagnosis (all patients)(Day of SAB diagnosis until day 90 after diagnosis)
- 90-day mortality because of SAB complications(Day of SAB diagnosis until day 90 after diagnosis)
- Hospital readmission until day 30 after SAB diagnosis (all patients)(Day of SAB diagnosis until day 30 after diagnosis)
- Hospital readmission until day 30 after SAB diagnosis (because of SAB complications)(Day of SAB diagnosis until day 30 after diagnosis)
- Relapse of bacteremia until day 90 after diagnosis(Day of SAB diagnosis until day 90 after diagnosis)
- Hospital readmission until day 90 after SAB diagnosis (because of SAB complications)(Day of SAB diagnosis until day 90 after diagnosis)
- 90-day all-cause mortality(Day of SAB diagnosis until day 90 after diagnosis)
- Quality of discharge summary (documentation and treatment plan), calculated as a sum score(Hospital admission until hospital discharge (no later than day 90 after diagnosis))
- Infectious diseases consultation, when indicated (yes/no)(Hospital admission until hospital discharge (no later than day 90 after diagnosis))