NCT01333007已完成不适用
A Cohort Study of First-line Treatment of Patients With Unresectable Advanced (Stage IIIB), Metastatic (Stage IV) or Recurrent Non Squamous Non-small Cell Lung Cancer (NSCLC), Starting a Treatment With Bevacizumab (Avastin®) in Combination With Chemotherapy.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 423
- 主要终点
- Progression-free survival
研究概览
简要总结
This observational study will evaluate modality, efficacy and safety of Avastin (bevacizumab) as first-line treatment in combination with chemotherapy in patients with inoperable advanced, metastatic or recurrent non-squamous non-small cell lung cancer in clinical practice. Data will be collected for each patient for 18 months from initiation of Avastin therapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients, >/= 18 years of age
- •Inoperable advanced, metastatic or recurrent non-squamous non-small cell lung cancer (NSCLC)
- •Treating physician's decision to initiate first-line Avastin treatment
排除标准
- •Participation in a clinical trial evaluating anti-cancer therapies
结局指标
主要结局
Progression-free survival
时间窗: 18 months
次要结局
- Overall survival(18 months)
- Quality of Life: Functional Assessment of Cancer Therapy-Lung (FACT-L) questionnaire(18 months)
- Clinical (diagnosis, therapies, comorbidity) and demographic characteristics of patients initiated on Avastin treatment(18 months)
- Treatment of non-squamous NSCLC in clinical practice(18 months)
- Modality of treatment with Avastin (dose, duration, associated chemotherapy)(18 months)
- Safety: Incidence of adverse events(18 months)
研究者
相似试验
已完成
不适用
An Observational Study of Avastin (Bevacizumab) in Elderly Patients With Non-Squamous Non-Small Cell Lung Cancer in Clinical PracticeNon-Squamous Non-Small Cell Lung CancerNCT01893268Hoffmann-La Roche279
已完成
不适用
An Observational Study of Avastin (Bevacizumab) in First Line in Patients With Metastatic Colorectal Cancer (AVANiS)Colorectal CancerNCT01674907Hoffmann-La Roche27
已完成
不适用
An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer (RELEVANT)Colorectal CancerNCT01697449Hoffmann-La Roche191
已完成
不适用
An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer (ACORN)Colorectal CancerNCT01506167Hoffmann-La Roche719
已完成
不适用
A Study of Avastin With Chemotherapy for Treatment of Metastatic or Advanced and Unresectable Colorectal AdenocarcinomaColorectal CancerNCT00097578Genentech, Inc.1,953