Effect of Dual Site-Dual Channel Non-invasive Brain Stimulation for Recovery of Language and Cognitive Function in Healthy Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 1
- 主要终点
- Verbal 3 back test
研究概览
简要总结
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of language and cognitive function in healthy. Simultaneous dual site-dual channel stimulation was applied by using two sets of transcranial direct current stimulation devices. All subjects will go through four conditions of transcranial direct current stimulation with for 30 minutes. Four conditions are 1) Dual stimulation: i) anodal stimulation on left inferior frontal cortex, ii) anodal stimulation on left dorsolateral prefrontal cortex. 2) IFG stimulation: anodal stimulation on left inferior frontal cortex; 3) DLPFC stimulation: anodal stimulation on left dorsolateral prefrontal cortex area. 4) sham stimulation
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy subjects with age over 19 years old
排除标准
- •history of disorders involving central nervous system
- •patients with severe medical or psychiatric disease
研究组 & 干预措施
Dual stimulation
i) anodal stimulation of left inferior frontal cortex ii) anodal stimulation on left dorsolateral prefrontal cortex
干预措施: IFG stimulation (Device)
Dual stimulation
i) anodal stimulation of left inferior frontal cortex ii) anodal stimulation on left dorsolateral prefrontal cortex
干预措施: DLPFC stimulation (Device)
IFG stimulation
anodal stimulation of left inferior frontal cortex
干预措施: IFG stimulation (Device)
DLPFC stimulation
anodal stimulation on left dorsolateral prefrontal cortex
干预措施: DLPFC stimulation (Device)
Sham stimulation
sham stimulation
干预措施: Sham stimulation (Device)
结局指标
主要结局
Verbal 3 back test
时间窗: Baseline and after intervention (approximately 30 minutes)
measure working memory
Korean Boston naming test
时间窗: Baseline and after intervention (approximately 30 minutes)
measures naming ability thorough picture naming test
次要结局
- Korean Color Word Stroop test(Baseline and after intervention (approximately 30 minutes))
- Controlled Oral Word Association Test(Baseline and after intervention (approximately 30 minutes))