Evaluation of Protein Requirements in Active, Young Adult Males
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 7
- 主要终点
- 13CO2 (carbon dioxide) excretion (μmol/kg/h)
研究概览
简要总结
Protein requirements in active individuals have been suggested to be greater than the current recommended dietary allowance (RDA).
Nutritional requirements for dietary amino acids in adults have traditionally been determined utilizing the nitrogen balance technique, which is prone to underestimating protein requirements. As a result, there is a need to re-evaluate recommendations in order to characterize how dietary amino acid needs may be modulated by physical activity.
Recent studies using the minimally invasive indicator amino acid oxidation (IAAO) technique have suggested that protein requirements in young men are at least 50% higher than the RDA based on nitrogen balance data.
The purpose of this study is to measure the protein requirement in active, young adult males using the IAAO technique in the presence of a variable intensity exercise stimulus.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy, active, young adult males who regularly participate in moderate-vigorous activity 5x per week, for a minimum of 1 hour
- •A minimum score of 10 on the Beep Test (a measure of aerobic fitness)
排除标准
- •Inability to meet health and physical activity guidelines according to the physical activity readiness questionnaire (PAR-Q+)
- •Inability to adhere to any of the protocol guidelines (i.e. alcohol, caffeine consumption)
- •Regular tobacco use
- •Illicit drug use
研究组 & 干预措施
Active, Young Adult Males
Subjects will receive different levels of amino acid intakes varying from 0.2 to 2.6 g/kg/day.
干预措施: Amino Acid Intake (Dietary Supplement)
结局指标
主要结局
13CO2 (carbon dioxide) excretion (μmol/kg/h)
时间窗: 4 hours / study day
次要结局
- 13C-Phenylalanine Oxidation (μmol/kg/h)(4 hours / study day)
研究者
Daniel Moore
Assistant Professor
University of Toronto