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临床试验/NCT00783159
NCT00783159已完成不适用

The Effect of Different Training Modalities and Vitamin D Supplementation on Functionality in Prefrail Elderly Persons

University of Erlangen-Nürnberg Medical School1 个研究点 分布在 1 个国家目标入组 69 人开始时间: 2008年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
69
试验地点
1
主要终点
Short physical performance battery

研究概览

简要总结

This intervention study tests training methods to stabilize or improve functionality in the high risk group of prefrail elderly persons.

详细描述

This study aims at the improvement of muscular function by physical exercise in prefrail elderly persons. Prefrail participants are recruited according to the frailty score of Fried. Taking into account, that vitamin D supplementation reduces falls and improves muscle strength in older people, all participants are supplemented by vitamin D. Two different training methods are tested.

After a run-in period of supplementation of vitamin D for two months, participants will be randomized into three different equally sized groups (n=25): Group A will receive power training. Group B will have progressive strength training. Group C will serve as a control group. They will receive a consultation about leading a healthy life with special attention being paid to nutrition and physical activity. The intervention period lasts for 12 weeks. The 60 minutes training sessions will be held two times a week by members of the Institute of Sport Science and Sports of the University of Erlangen-Nuremberg. Follow-up visits are scheduled three and six months after intervention period.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Prefrailty according to the frailty score of Fried

排除标准

  • •Sarcoidosis
  • •Nephrolithiasis
  • •Plasmacytoma
  • •Inflammatory bowel disease
  • •Rheumatoid arthritis
  • •History of cancer
  • •Instable heart disease
  • •Depression (GDS>=6)
  • •Dementia (MMSE<=24)
  • •BMI>35kg/m²
  • •Current attendance of muscle training
  • •Medication: immunosuppressive drugs

研究组 & 干预措施

A

Experimental

Training I

干预措施: Power Training (Procedure)

B

Experimental

Training II

干预措施: Strength Training (Procedure)

C

Active Comparator

Control

干预措施: Control (Other)

结局指标

主要结局

Short physical performance battery

时间窗: 3 months after intervention

次要结局

  • Muscle strength and muscle power(3 months after intervention)

研究者

发起方
University of Erlangen-Nürnberg Medical School
申办方类型
Other
责任方
Sponsor

研究点 (1)

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