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临床试验/NCT04969640
NCT04969640已完成不适用

Role of Anterior Segment Optical Coherence Tomography in Staging and Evaluation of Treatment Response in Infectious Keratitis

Minia University1 个研究点 分布在 1 个国家目标入组 23 人开始时间: 2021年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
23
试验地点
1
主要终点
width of lesion on optical coherence tomography

研究概览

简要总结

To evaluate the role of anterior segment optical coherence tomography in follow up of infectious keratitis and assessment of response to treatment.

详细描述

50 patients with proven infectious keratitis clinically will be included in the study.

The following will be performed for all patients in initial visit and follow up:

  • Slit lamp examination and photography.
  • Visual acuity assessment.
  • Anterior segment optical coherence tomography.
  1. The central corneal thickness (CCT) (extracted from pachymetry map),
  2. Minimal corneal thickness (MCT) (extracted from pachymetry map)
  3. Corneal thickness at the site of the lesion (CTL) (extracted from pachymetry map or the sum of STL+ CETL)
  4. Stromal thickness at the center of the lesion (STL) stromal lesion (extracted from stromal map)
  5. Corneal epithelial thickness over the stromal lesion (CETL) at the center of the lesion (extracted from epithelial map)

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • Any case with infectious keratitis (any age) either received medical treatment or not, attending to our department will be included in the study.

排除标准

  • Cases with healed infectious keratitis.
  • Cases presented from the start with severe corneal affection and melting.

结局指标

主要结局

width of lesion on optical coherence tomography

时间窗: 1 month

width of infiltration in microns

criteria of lesion on optical coherence tomography

时间窗: 1 month

Localiztion, depth of infiltration area in microns

次要结局

未报告次要终点

研究者

发起方
Minia University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahemd Abdelghany

Assistant professor

Minia University

研究点 (1)

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