NCT04969640已完成不适用
Role of Anterior Segment Optical Coherence Tomography in Staging and Evaluation of Treatment Response in Infectious Keratitis
Minia University1 个研究点 分布在 1 个国家目标入组 23 人开始时间: 2021年7月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 23
- 试验地点
- 1
- 主要终点
- width of lesion on optical coherence tomography
研究概览
简要总结
To evaluate the role of anterior segment optical coherence tomography in follow up of infectious keratitis and assessment of response to treatment.
详细描述
50 patients with proven infectious keratitis clinically will be included in the study.
The following will be performed for all patients in initial visit and follow up:
- Slit lamp examination and photography.
- Visual acuity assessment.
- Anterior segment optical coherence tomography.
- The central corneal thickness (CCT) (extracted from pachymetry map),
- Minimal corneal thickness (MCT) (extracted from pachymetry map)
- Corneal thickness at the site of the lesion (CTL) (extracted from pachymetry map or the sum of STL+ CETL)
- Stromal thickness at the center of the lesion (STL) stromal lesion (extracted from stromal map)
- Corneal epithelial thickness over the stromal lesion (CETL) at the center of the lesion (extracted from epithelial map)
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any case with infectious keratitis (any age) either received medical treatment or not, attending to our department will be included in the study.
排除标准
- •Cases with healed infectious keratitis.
- •Cases presented from the start with severe corneal affection and melting.
结局指标
主要结局
width of lesion on optical coherence tomography
时间窗: 1 month
width of infiltration in microns
criteria of lesion on optical coherence tomography
时间窗: 1 month
Localiztion, depth of infiltration area in microns
次要结局
未报告次要终点
研究者
Ahemd Abdelghany
Assistant professor
Minia University
研究点 (1)
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