NCT02164448已完成4 期
The Effects of Intraoperative Dexmedetomidine Infusion on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 92
- 试验地点
- 1
- 主要终点
- gas passing
研究概览
简要总结
The investigators hypothesized that sympatholytic effect of dexmedetomidine would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery. This study is to investigate the effect of intraoperative dexmedetomidine infusion on postoperative bowel movement in patients undergoing laparoscopic gastrectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient between 20 and 65 of age with ASA physical status Ⅰ-Ⅲ
- •gastric cancer patient undergoing laparoscopic gastrectomy
排除标准
- •ASA physical status Ⅳ
- •bradycardia (< 60 bpm), arrhythmia
- •uncompensated heart failure
- •hepatic failure (Child-Pugh score B 이상)
- •renal failure (eGFR MDRD < 60 ml/min/1.73m2)
研究组 & 干预措施
dexmedetomidine group
Experimental
干预措施: the dexmedetomidine group (Drug)
control group
Placebo Comparator
干预措施: the control group (Drug)
结局指标
主要结局
gas passing
时间窗: up to 1 week
To evaluate the postoperative bowel movement, we will assess the time to first gas passing
次要结局
- sips of water time(up to 1 week)
研究者
研究点 (1)
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