Reconstructing sentence processing in aphasia: Unification Therapy Integrating LexIcon and Sentences

niversity College London0 个研究点目标入组 34 人开始时间: 2019年9月13日最近更新: 2024年3月25日

试验速览

2021 Other publications in https://pubmed.ncbi.nlm.nih.gov/34357663/ case series report (added 21/10/2021)

•Current inclusion criteria as of 09/03/2020:
•1. Premorbid competence in English
•2. Premorbidly right-handed
•3. Single left hemisphere stroke
•4. At least 6 months post-stroke onset
•5. Presence of aphasia, characterized by spoken sentence comprehension impairment (scoring < 16 blocks correct on TROG-2) and/or spoken sentence production difficulties (incomplete and/or simple sentences) at baseline assessment
•6. Capacity to give informed consent
•7. Sufficient auditory and visual capacity to interact with the behavioural therapy
•Previous inclusion criteria:
•1. Premorbid competence in English
•2. Premorbidly right-handed
•3. Single left hemisphere stroke
•4. At least 6 months post-stroke onset
•5. Presence of aphasia, characterized by spoken and written comprehension impairment and spoken sentence production difficulties
•6. Capacity to give informed consent
•7. Sufficient auditory and visual capacity to interact with the behavioural therapy

•Current participant exclusion criteria as of 21/10/2021:
•1. Significant other neurological disorder (e.g., neurodegenerative illness)
•2. History of speech and language disorder prior to stroke (e.g., developmental dyslexia)
•3. Current involvement in another therapy trial
•Previous participant exclusion criteria as of 09/03/2020:
•1. Significant other neurological disorder (e.g., neurodegenerative illness)
•2. History of speech and language disorder prior to stroke (e.g., developmental dyslexia)
•3. Current involvement in another brain stimulation or behavioural therapy trial
•4. Metal implants on/in head causing tDCS risk and heart pacemakers
•5. History of severe headaches requiring treatment with medication other than simple analgesia
•6. History of seizure in the past 6 months
•7. Headscarf or hairstyle that prevents contact between electrode and skin
•8. Skin abrasion/abnormality below the site of the electrodes
•9. Adverse effects to previous tDCS or other brain stimulation techniques
•10. Pregnant or likely to be pregnant
•Previous exclusion criteria:
•1. Significant other neurological disorder (e.g., neurodegenerative illness)
•2. History of speech and language disorder prior to stroke (e.g., developmental dyslexia)
•3. Metal implants on/in head causing tDCS risk
•4. Recurring headaches
•5. History of seizure in the past 3 months
•6. Current involvement in another brain stimulation or behavioural therapy trial

发起方

niversity College London