Anti-inflammatory Therapy Following Selective Laser Trabeculoplasty (SLT): A Randomized, Masked, Placebo Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Intraocular pressure lowering effect
研究概览
简要总结
The type of anti-inflammatory medication used post selective laser trabeculoplasty (SLT) may have an impact on the intra-ocular pressure (IOP) lowering effect of SLT. This study will evaluate the IOP lowering effect of SLT following the topical administration of one of the following: prednisolone 1%, ketorolac 0.5% or artificial tears.
详细描述
Patients who have been chosen to undergo SLT for glaucoma will be randomized to receive one of prednisolone 1%, ketorolac 0.5% or artificial tears four times a day for 5 days following administration of the laser treatment. The IOP will be measured at various time points following SLT: 1 hour, 2 days, 1 week, 1 month, 3 months, 6 months, and 1 year.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •primary open angle glaucoma, pseudo exfoliation glaucoma
排除标准
- •previous incisional glaucoma surgery
研究组 & 干预措施
1
Prednisolone 1% eye drop
干预措施: prednisolone 1% (Drug)
2
ketorolac 0.5% eye drop
干预措施: ketorolac 0.5% (Drug)
3
Artificial Tears (methyl cellulose eye drop)
干预措施: Artificial Tears (Methyl cellulose drops) (Drug)
结局指标
主要结局
Intraocular pressure lowering effect
时间窗: 1 hour, 2 days, 1 month, 3 months, 6 months and 1 year
次要结局
- intraocular pressure elevation(1 hour, 2 days, 1 month)
研究者
Dr. Robert Campbell
Assistant Professor
Queen's University