Non-invasive vs Invasive Cardiac Output Monitoring in Patients Under Spinal Anesthesia During Cesarean Section: a Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 主要终点
- Cardiac output (CO)
研究概览
简要总结
This study aims to evaluate the consistency of hemodynamic monitoring between NICAP and NICCO technologies (T20A; Chongqing, China) and the traditional pulse wave analysis method (EV1000; USA).
详细描述
The uterine placenta lacks autonomous regulatory ability, thus making maternal cardiac output (CO) the primary source of blood supply. Therefore, monitoring hemodynamics, including maternal CO, is of significant importance and provides guidance for anesthesia decisions such as fluid management and the administration of vasopressors during cesarean section. This study aims to evaluate the consistency of hemodynamic monitoring between NICAP and NICCO technologies (T20A; Chongqing, China) and the traditional pulse wave analysis method (EV1000; USA).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •18-45 years
- •Primipara or multipara
- •Singleton pregnancy ≥37 weeks
- •American Society of Anesthesiologists physical status classification I to II
- •Scheduled for cesarean section under spinal anesthesia
排除标准
- •Body height < 150 cm
- •Body weight > 100 kg or body mass index (BMI) ≥ 40 kg/m2
- •Eclampsia or chronic hypertension or baseline blood pressure ≥140 mmHg
- •Hemoglobin < 7g/dl
- •Fetal distress, or known fetal developmental anomaly
结局指标
主要结局
Cardiac output (CO)
时间窗: 1-60 minutes after spinal anesthesia
Monitoring data
Cardiac index (CI)
时间窗: 1-60 minutes after spinal anesthesia
Monitoring data
Stroke volume variation (SVV)
时间窗: 1-60 minutes after spinal anesthesia
Monitoring data
Stroke volume (SV)
时间窗: 1-60 minutes after spinal anesthesia
Monitoring data
Peripheral vascular resistance
时间窗: 1-60 minutes after spinal anesthesia
Monitoring data
次要结局
- The incidence of bradycardia(1-15 minutes after spinal anesthesia)
- The incidence of severe post-spinal anesthesia hypotension(1-15 minutes after spinal anesthesia)
- The incidence of nausea and vomiting.(1-15 minutes after spinal anesthesia)
- The incidence of hypertension(1-15 minutes after spinal anesthesia)
- The incidence of post-spinal anesthesia hypotension(1-15 minutes after spinal anesthesia.)