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临床试验/NCT07489417
NCT07489417招募中不适用

Impact of Sleep Restriction on Blood Pressure Reactivity

University of Missouri-Columbia1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2026年3月4日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
45
试验地点
1
主要终点
Mean Blood Pressure

研究概览

简要总结

The purpose of the research study is to examine the effects of shortened sleep on blood pressure.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy adult men and women
  • 18-45 years of age
  • BMI < 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group)
  • Non-pregnant, non-breastfeeding, and non-nicotine users
  • Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight
  • Premenopausal

排除标准

  • No acute or chronic conditions
  • Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function
  • Self-reported history of irregular sleep
  • Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension

研究组 & 干预措施

Sleep Restriction

Experimental

You will be asked to shorten your sleep to four hours.

干预措施: Sleep Restriction (Behavioral)

Normal Sleep

No Intervention

You will be asked to sleep for 7-9 hours.

结局指标

主要结局

Mean Blood Pressure

时间窗: Baseline and during the last 1-minute of stress

Mean Blood pressure

Blood Pressure

时间窗: Baseline and during the last 1-minute of stress

Blood pressure

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jacqueline K Limberg, PhD

Associate Professor

University of Missouri-Columbia

研究点 (1)

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