Evaluation of Induced Endometrial Injury in the Subsequent IVF Cycle.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 600
- 试验地点
- 2
- 主要终点
- Ongoing implantation rate (OIR)
研究概览
简要总结
Some studies have revealed that an induced endometrial injury could improve embryo human implantation in patients with implantation failure.
The purpose of this study is to determine whether the induced endometrial injury could be beneficial for regular patients undergoing IVF
详细描述
Endometrial induced injury has been suggested that could improve embryo implantation in cases of patients with recurrent implantation failure. The mechanisms that induce that improvement remain unknown.
We want to analyse if the endometrial induce injury could be useful in cases of standard patients who require assisted reproductive techniques.
For that purpose we will start a randomized controlled trial with the ideal background in implantation in ART, the egg donation programme.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 44 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •19-44 aged women
- •19-29.9 Kg/m
- •1st or 2nd fresh embryo transfer ( egg donation).
- •1 or 2 blastocysts available.
- •written agreement.
- •> or = 6 mms endometrial thickness.
排除标准
- •Premature ovarian failure.
- •Endometrial pathology.
- •Insufficient endometrial development.
- •Hydrosalpinx
- •Mullerian malformations.
结局指标
主要结局
Ongoing implantation rate (OIR)
时间窗: 12 weeks of pregnancy
次要结局
- Live born rate (LBR)(9 months after embryo transfer)
研究者
Carmina Vidal, MD
Obstetrics and Gynecology
Instituto Valenciano de Infertilidad, IVI VALENCIA