NCT05726877招募中不适用
Determination of Optimal Positive End-expiratory Pressure in Prone Position During General Anesthesia Using Electrical Impedance Tomography in Pediatric Patient Under 17 Years of Age
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 51
- 试验地点
- 1
- 主要终点
- Optimal positive end-expiratory pressure (PEEP)
研究概览
简要总结
This study aimed to investigate the differences in positive end-expiratory pressure titration in the supine and prone positions by age in pediatric patients under 17 years of age who received general anesthesia and then evaluate the hemodynamic stability.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 0 Years 至 16 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who are scheduled to undergo general anesthesia in the prone position
- •patients who are in age under 17 years
排除标准
- •had cyanosis or chronic respiratory failure
- •had respiratory distress syndrome or bronchopulmonary dysplasia
- •had laryngotracheal diseases
- •had pulmonary hypertension
- •receiving oxygen therapy
结局指标
主要结局
Optimal positive end-expiratory pressure (PEEP)
时间窗: 60 minutes after prone positioning
result of decremental PEEP trial
次要结局
- Impedance tidal variation(60 minutes after prone positioning)
- overdistension or atelectasis(60 minutes after prone positioning)
- regional ventilation delay(60 minutes after prone positioning)
- arterial blood gas analysis, if patients has arterial catheter(10 minutes after intubation & 60 minutes after prone positioning)
- end-expiratory lung impedance(60 minutes after prone positioning)
- center of ventilation(60 minutes after prone positioning)
- end-expiratory lung volume(60 minutes after prone positioning)
- regional respiratory system compliance(10 minutes after intubation)
- vital signs(60 minutes after prone positioning)
研究者
研究点 (1)
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