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临床试验/NCT02365363
NCT02365363已完成不适用

Pulse EnRiched Food and Exercise Clinical Trials (PERFECT Project): Part 2 - Acute Effects of Pulse Ingredients in Food Products on Aerobic Endurance and Substrate Oxidation During Exercise, as Well as, the Blood Glucose, Insulin, Lactate and Food Intake Response Following an Endurance Exercise Session in Adults - Study 3

University of Manitoba1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2016年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
1
主要终点
Plasma Glucose and Insulin Concentrations

研究概览

简要总结

The objectives are to test the acute effects of different bagels containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic exercise session, and 3) food intake two hours following the exercise session. We hypothesize that consumption of bagels containing pulse ingredients 60 minutes before exercise will increase aerobic endurance (lower oxygen consumption), decrease carbohydrate oxidation (greater respiratory quotient), and a reduction in lactate production during compared to the same exercise session following the ingestion of a non-pulse food. We also hypothesize that consumption of bagels containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake, suggesting lower calorie compensation, following a 60-minute aerobic exercise session compared to the same exercise session following the ingestion of a non-pulse food.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Normoglycemic (<5.6 mmol/L) and normotensive (systolic blood pressure <140 mm Hg and diastolic blood pressure below < 90 mm Hg)
  • BMI of 18.5-29.9 kg/m2

排除标准

  • Restrained eaters
  • Regularly skip breakfast
  • Those who are active (organized activities or athletic training at a high intensity; ≥ 150 min per week of moderate to vigorous physical activity)
  • Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year
  • Those unable to walk for an hour continuously

研究组 & 干预措施

Bagel with pea flour

Experimental

Pea flour (30%)

干预措施: Pea flour (Other)

Bagel with pea fibre

Experimental

Pea fibre (11g)

干预措施: Pea fibre (Other)

Bagel control

Experimental

100% wheat flour

干预措施: Control (Other)

Bagel w/ pea flour + pea fibre

Experimental

Pea flour (30%) + pea fibre (11g)

干预措施: Pea flour and pea fibre (Other)

Bagel w/ pea flour + pea protein

Experimental

Pea flour (30%) + pea protein (24g)

干预措施: Pea flour and pea protein (Other)

Bagel w/ pea flour + pea fibre + pea protein

Experimental

Pea flour (30%) + pea fibre (11g) + pea protein (24g)

干预措施: Pea flour + pea fibre + pea protein (Other)

结局指标

主要结局

Plasma Glucose and Insulin Concentrations

时间窗: 0-240

Measured in blood using intravenous catheter. Glucose will be determined by automated methods using Abbot Spectrum CCX Analyzer, and Insulin will be measured by commercially available RIA kits

Food Intake

时间窗: 120 min

Ad-libitum meal

Subjective Appetite

时间窗: 0-240 min

Motivation-to-eat VAS questionnaire

Exercise intensity

时间窗: 60-120 min

Oxygen consumption measured during exercise at 3 time points

次要结局

  • Palatability(5 and 260 min)
  • Lactate concentration(60-120 min)
  • Substrate Oxidation(60-120 min)
  • Energy/fatigue(0 - 240 min)
  • Heart rate(60-120 min)
  • Physical comfort(0-240 min)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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